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Nucleotide sequence of a cDNA coding for the mitochondrial precursor protein of cytochrome c oxidase subunit IV from the slime mold Dictyostelium discoideum.

作者信息

Rizzuto R, Sandonà D, Capaldi R A, Bisson R

机构信息

CNR Centro Studi per la Fisiologia dei Mitocondrie, Università di Padova, Italy.

出版信息

Biochim Biophys Acta. 1991 Aug 27;1090(1):125-8.

PMID:1653019
Abstract

Subunit-specific polyclonal antibodies were used to isolate cDNA clones encoding subunit IV of Dictyostelium discoideum cytochrome c oxidase. DNA sequence analysis reveals an open reading frame of 149 amino acids. As shown by sequencing of the protein N-terminus, the subunit is synthesized with a 24 residue cleavable presequence which leads to a mature polypeptide of 14305 Da. The slime mold subunit exhibits a low but significant degree of similarity with subunit Va of human and subunit VI of yeast cytochrome c oxidase.

摘要

相似文献

1
Nucleotide sequence of a cDNA coding for the mitochondrial precursor protein of cytochrome c oxidase subunit IV from the slime mold Dictyostelium discoideum.
Biochim Biophys Acta. 1991 Aug 27;1090(1):125-8.
2
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3
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Subunits I and II of Dictyostelium cytochrome c oxidase are specified by a single open reading frame transcribed into a large polycistronic RNA.盘基网柄菌细胞色素c氧化酶的亚基I和亚基II由转录成大的多顺反子RNA的单一开放阅读框所编码。
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