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纤维支气管镜检查在小细胞肺癌化疗前及化疗期间对评估完全缓解的重要性。

Importance of fiberoptic bronchoscopy before and during chemotherapy for small cell carcinoma of the lung in the evaluation of complete remission.

作者信息

Wang J S, Lia S L, Perng R P

机构信息

Department of Chest Medicine, Veterans General Hospital-Taipei, R.O.C.

出版信息

Zhonghua Yi Xue Za Zhi (Taipei). 1991 Jul;48(1):41-4.

PMID:1653091
Abstract

The aim of our study was to evaluate the role of fiberoptic bronchoscopy both in diagnosing patients with small cell lung carcinoma and in assessing complete remission following combination chemotherapy. Although there were 90 patients in this study, 33 patients received the complete restaging procedure. Initially at diagnosis, all lesions seen through the bronchoscopy were localized to central bronchi in 22 patients. In the other 10 patients there was either bronchial distortion or abnormal mucosal appearance. In the last one no endoscopic lesion was assessed. Following combination chemotherapy complete remission in 12 patients was assessed by comparing the findings at repeat fiberoptic bronchoscopy with those of chest radiology. In this study, three (25%) of 12 patients with negative radiological patterns were still affected by the tumor at fiberoptic bronchoscopy. The higher reliability of fiberoptic bronchoscopy than that of standard chest X-ray is emphasized.

摘要

我们研究的目的是评估纤维支气管镜检查在诊断小细胞肺癌患者以及评估联合化疗后完全缓解情况中的作用。尽管本研究中有90例患者,但33例患者接受了完整的再分期程序。最初在诊断时,通过支气管镜检查发现的所有病变在22例患者中局限于中央支气管。在其他10例患者中,存在支气管扭曲或黏膜外观异常。在最后1例患者中,未评估到内镜下病变。联合化疗后,通过将重复纤维支气管镜检查结果与胸部放射学结果进行比较,评估了12例患者的完全缓解情况。在本研究中,12例放射学表现为阴性的患者中有3例(25%)在纤维支气管镜检查时仍有肿瘤影响。强调了纤维支气管镜检查比标准胸部X线检查具有更高的可靠性。

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Importance of fiberoptic bronchoscopy before and during chemotherapy for small cell carcinoma of the lung in the evaluation of complete remission.纤维支气管镜检查在小细胞肺癌化疗前及化疗期间对评估完全缓解的重要性。
Zhonghua Yi Xue Za Zhi (Taipei). 1991 Jul;48(1):41-4.
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