Grandin W, Dessieux T, Hounfodji P, Viquesnel G, Ouchikhe A, Gérard J-L
Département d'Anesthésie-Réanimation Chirurgicale-Samu, Centre Hospitalier Régional et Universitaire de Caen, avenue de la Côte-de-Nacre, 14033 Caen cedex, France.
Ann Fr Anesth Reanim. 2006 May;25(5):521-4. doi: 10.1016/j.annfar.2005.12.007. Epub 2006 Mar 10.
Mucormycosis are opportunist infections occurring usually among predisposed patients. We report a case of an 18-year-old male with a severe thoracic trauma who developed an Absidia infection on his contused pulmonary parenchyma, without presenting the usual risk factors (diabetes mellitus, immunodeficiency). The early diagnosis using bronchoscopy has probably improved the outcome by allowing a faster treatment. After 18-months, the infectious process resolved thanks to a combination of a medical treatment composed of high-dose amphotericin B lipid formulation, itraconazole and a complementary surgical treatment.
毛霉病是一种通常发生在易感患者中的机会性感染。我们报告一例18岁男性严重胸部创伤患者，其挫伤的肺实质发生了犁头霉感染，且未出现常见的危险因素（糖尿病、免疫缺陷）。通过支气管镜进行早期诊断，可能因得以更快治疗而改善了预后。18个月后，由于采用高剂量两性霉素B脂质体剂型、伊曲康唑组成的药物治疗与辅助手术治疗相结合，感染过程得以解决。
