Vedantham Vasumathy, Nirmalan Praveen K, Ramasamy Kim, Prakash Karthik, Namperumalsamy Perumalsamy
Aravind Eye Hospital and PG Institute of Ophthalmology, 1, Anna Nagar, Madurai, TamilNadu-625 020, India.
Indian J Ophthalmol. 2006 Mar;54(1):5-10. doi: 10.4103/0301-4738.21607.
To analyze the clinical and microbiological characteristics of eyes with post-traumatic endophthalmitis and factors influencing the visual outcomes in these cases.
We performed a retrospective chart analysis of the clinical and microbiological data of 97 consecutive patients with post-traumatic endophthalmitis presenting to a tertiary eye care hospital in South India.
Thirty-nine (40.2%) cases were culture-positive, gram-positive cocci (n=24/42, 57.1%) being the commonest isolates. Staphylococcus epidermidis and Pseudomonas aeuruginosa were the commonest single isolates (n=10; 23.8%). Majority of the organisms were sensitive to chloramphenicol (n=27) or ciprofloxacin (n=26). Susceptibility to vancomycin (n=3) and amikacin (n=4) was poor. Cases with negative cultures at presentation were more likely to have improvement in visual acuity compared with culture-positive cases (on multivariate analysis, OR: 3.2, 95% CI: 1.1, 9.0).
In this series of post-traumatic endophthalmitis, a high prevalence of resistance of the culture isolates to vancomycin and amikacin was observed.
分析外伤性眼内炎患者的临床和微生物学特征以及影响这些病例视觉预后的因素。
我们对印度南部一家三级眼科护理医院连续收治的97例外伤性眼内炎患者的临床和微生物学数据进行了回顾性图表分析。
39例（40.2%）培养阳性，革兰氏阳性球菌（n=24/42，57.1%）是最常见的分离菌。表皮葡萄球菌和铜绿假单胞菌是最常见的单一分离菌（n=10；23.8%）。大多数微生物对氯霉素（n=27）或环丙沙星（n=26）敏感。对万古霉素（n=3）和阿米卡星（n=4）的敏感性较差。与培养阳性病例相比，就诊时培养阴性的病例视力改善的可能性更大（多因素分析，OR：3.2，95%CI：1.1，9.0）。
在这一系列外伤性眼内炎病例中，观察到培养分离菌对万古霉素和阿米卡星的耐药率较高。
