Xu Ying, Li Yan, Xu Gaixia, Qin Lifeng, Li Rong, Ye Xuesong, Wang Ping
Biosensors National Special Lab, Department of Biomedical Engineering, Zhejiang University. Hangzhou 310027, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2006 Feb;23(1):216-9.
This paper introduces the new research achievement and progress of electro-physiology in olfaction and gustation. Classical implements such as patch-clamp or glass pipette are not appropriate in the dynamic detection of cellular signal transportation. In view of this, we have analyzed the feasibilities and challenges of olfactory or gustatory cell-based biosensors such as field effect transistor (FET) and light addressable potentiometric sensor (LAPS). Finally we present the research work carried our in out lab and a future prospective on the development in this field.
本文介绍了嗅觉和味觉电生理学的新研究成果与进展。传统工具如膜片钳或玻璃微电极不适用于细胞信号传递的动态检测。鉴于此,我们分析了基于嗅觉或味觉细胞的生物传感器(如场效应晶体管(FET)和光寻址电位传感器(LAPS))的可行性与挑战。最后,我们展示了在我们实验室开展的研究工作以及该领域未来发展的展望。