Messieha Z S, Ananda R C, Hoffman W E, Punwani I C, Koenig H M
Department of Anesthesiology, University of Illinois, Chicago, Ill, USA.
Pediatr Dent. 2005 Nov-Dec;27(6):500-4.
Pediatric oral rehabilitation patients who receive presedation with oral Versed and general anesthesia (GA) occasionally experience prolonged sedation and delayed discharge. The Bispectral Index System (BIS) is an EEG monitor that measures the anesthesia level. The purpose of this study was to compare the effects of monitoring the BIS to not monitoring the BIS on time from discontinuation of GA to extubation and to discharge.
Twenty-nine children were enrolled. BIS was monitored from admission until discharge. Each child received 0.7 mg/kg of oral Versed. In the operating room, GA with sevoflurane (IH), rocuronium 1 mg/kg (IV), fentanyl 1 microg/kg (IV), and ondansetron 0.15 mg/kg (IV) was administered. Randomly, in half the patients, the anesthesiologist maintained the level of anesthesia and BIS by adjusting sevoflurane. In the rest, the anesthesiologist did not know BIS. The time from turning off sevoflurane to discharge was compared.
Group 1 patients were extubated 5+/-2 minutes sooner than group 2 patients (P=.04). The post-anesthesia care unit stay for group 1 patients was 47+/-17 minutes compared to 63+/-17 minutes in group 2. (p=0.02).
Monitoring anesthesia with BIS promotes earlier extubation and discharge for pediatric dental patients who receive oral Versed and sevoflurane GA.
接受口服咪达唑仑预镇静和全身麻醉(GA)的小儿口腔康复患者偶尔会出现镇静时间延长和出院延迟的情况。脑电双频指数系统(BIS)是一种测量麻醉深度的脑电图监测仪。本研究的目的是比较监测BIS与不监测BIS对从GA停止到拔管及出院时间的影响。
纳入29名儿童。从入院到出院监测BIS。每个儿童接受0.7mg/kg的口服咪达唑仑。在手术室,给予七氟醚(吸入)、1mg/kg罗库溴铵(静脉注射)、1μg/kg芬太尼(静脉注射)和0.15mg/kg昂丹司琼(静脉注射)进行GA。随机地,在一半患者中,麻醉医生通过调整七氟醚维持麻醉水平和BIS。其余患者中,麻醉医生不知道BIS值。比较从停止使用七氟醚到出院的时间。
1组患者比2组患者拔管时间早5±2分钟(P = 0.04)。1组患者在麻醉后护理单元的停留时间为47±17分钟,而2组为63±17分钟(p = 0.02)。
对于接受口服咪达唑仑和七氟醚GA的小儿牙科患者,使用BIS监测麻醉可促进更早拔管和出院。