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用丙泊酚预防七氟烷引起的谵妄和躁动。

Prevention of sevoflurane delirium and agitation with propofol.

作者信息

Messieha Zakaria

机构信息

University of Illinois at Chicago, Chicago, Illinois, USA.

出版信息

Anesth Prog. 2013 Summer;60(2):67-71. doi: 10.2344/0003-3006-60.3.67.

DOI:10.2344/0003-3006-60.3.67
PMID:23763562
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3683883/
Abstract

Emergence delirium and agitation (EAD) associated with sevoflurane general anesthesia are very commonly observed in young children. Such events pose a risk for injury as well as decreased parental satisfaction, especially in the ambulatory and office-based setting. This article reviews the different approaches described in the literature to reduce EAD. A novel approach using a Bispectral Index System (BIS)-guided anesthesia with propofol washout technique is proposed as a viable and effective approach to prevent EAD.

摘要

与七氟醚全身麻醉相关的苏醒期谵妄和躁动(EAD)在幼儿中非常常见。此类事件会带来受伤风险以及降低家长满意度,尤其是在门诊和诊所环境中。本文回顾了文献中描述的减少EAD的不同方法。提出了一种使用脑电双频指数系统(BIS)引导麻醉并结合丙泊酚洗脱技术的新方法,作为预防EAD的一种可行且有效的方法。

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本文引用的文献

1
Acupuncture management of pain and emergence agitation in children after bilateral myringotomy and tympanostomy tube insertion.双侧鼓膜切开置管术后儿童疼痛及苏醒期躁动的针刺治疗
Paediatr Anaesth. 2009 Nov;19(11):1096-101. doi: 10.1111/j.1460-9592.2009.03129.x. Epub 2009 Aug 26.
2
Post-induction alfentanil reduces sevoflurane-associated emergence agitation in children undergoing an adenotonsillectomy.诱导后使用阿芬太尼可减少接受腺样体扁桃体切除术的儿童与七氟醚相关的苏醒期躁动。
Acta Anaesthesiol Scand. 2009 May;53(5):678-81. doi: 10.1111/j.1399-6576.2009.01943.x.
3
Effect of propofol on emergence behavior in children after sevoflurane general anesthesia.丙泊酚对七氟醚全身麻醉后儿童苏醒行为的影响。
Paediatr Anaesth. 2008 Jan;18(1):55-9. doi: 10.1111/j.1460-9592.2007.02376.x.
4
A single dose of propofol at the end of surgery for the prevention of emergence agitation in children undergoing strabismus surgery during sevoflurane anesthesia.在七氟醚麻醉下斜视手术患儿手术结束时给予单剂量丙泊酚以预防苏醒期躁动。
Anesthesiology. 2007 Nov;107(5):733-8. doi: 10.1097/01.anes.0000287009.46896.a7.
5
Sevoflurane directly excites locus coeruleus neurons of rats.七氟醚直接兴奋大鼠蓝斑神经元。
Anesthesiology. 2007 Dec;107(6):992-1002. doi: 10.1097/01.anes.0000291453.78823.f4.
6
Ketamine is effective in decreasing the incidence of emergence agitation in children undergoing dental repair under sevoflurane general anesthesia.氯胺酮可有效降低七氟醚全身麻醉下接受牙科修复的儿童出现苏醒期躁动的发生率。
Paediatr Anaesth. 2007 Sep;17(9):846-50. doi: 10.1111/j.1460-9592.2007.02298.x.
7
Physostigmine and anaesthesia emergence delirium in preschool children: a randomized blinded trial.
Eur J Anaesthesiol. 2008 Jan;25(1):37-42. doi: 10.1017/S0265021507001159. Epub 2007 Jul 26.
8
Midazolam does not reduce emergence delirium after sevoflurane anesthesia in children.咪达唑仑不能减少儿童七氟醚麻醉后的苏醒期谵妄。
Paediatr Anaesth. 2007 Apr;17(4):347-52. doi: 10.1111/j.1460-9592.2006.02101.x.
9
Dexmedetomidine decreases emergence agitation in pediatric patients after sevoflurane anesthesia without surgery.右美托咪定可减少小儿患者在未进行手术的七氟醚麻醉后的苏醒期躁动。
Paediatr Anaesth. 2006 Jul;16(7):748-53. doi: 10.1111/j.1460-9592.2006.01845.x.
10
Bispectral index system (BIS) monitoring reduces time to extubation and discharge in children requiring oral presedation and general anesthesia for outpatient dental rehabilitation.双谱指数系统(BIS)监测可缩短需要口服镇静剂和全身麻醉进行门诊牙科康复的儿童的拔管时间和出院时间。
Pediatr Dent. 2005 Nov-Dec;27(6):500-4.