吸入长效β2受体激动剂在哮喘管理中的作用。
The role of inhaled long-acting beta-2 agonists in the management of asthma.
作者信息
Kelly H William, Harkins Michelle S, Boushey Homer
机构信息
Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.
出版信息
J Natl Med Assoc. 2006 Jan;98(1):8-16.
Abstract
The role of inhaled beta-2 agonists in the management of asthma has changed significantly over the last several years. This review outlines the most recent understanding of the pathophysiology of asthma and the studies that define the roles that both short- and long-acting beta-2 agonists play in therapy for this disease. A concentration on the clinical pharmacology and genetic implications for clinical use of this class of drugs in accordance with the national and international guidelines are described.
摘要
在过去几年中，吸入性β-2激动剂在哮喘治疗中的作用发生了显著变化。本综述概述了对哮喘病理生理学的最新认识，以及确定短效和长效β-2激动剂在该疾病治疗中所起作用的研究。文中还描述了根据国家和国际指南，对这类药物临床药理学及临床应用遗传意义的关注。
相似文献
1
The role of inhaled long-acting beta-2 agonists in the management of asthma.吸入长效β2受体激动剂在哮喘管理中的作用。
J Natl Med Assoc. 2006 Jan;98(1):8-16.
2
Role of long-acting beta2-adrenergic agonists in asthma management based on updated asthma guidelines.基于最新哮喘指南的长效β2肾上腺素能激动剂在哮喘管理中的作用
Curr Opin Pulm Med. 2008 Jan;14(1):57-63. doi: 10.1097/MCP.0b013e3282f27121.
3
[Long acting beta-2 agonists in the treatment of asthma and their safety].长效β2受体激动剂在哮喘治疗中的应用及其安全性
Tuberk Toraks. 2011;59(4):409-15. doi: 10.5578/tt.3269.
4
5
Combination therapy with a long-acting beta2-agonist and an inhaled corticosteroid as initial maintenance treatment in asthma.长效β2受体激动剂与吸入性糖皮质激素联合治疗作为哮喘的初始维持治疗
Ann Allergy Asthma Immunol. 2005 Mar;94(3):410-1; author reply 411-2. doi: 10.1016/S1081-1206(10)60999-4.
6
Pharmacological management of asthma.哮喘的药物治疗
Aust Fam Physician. 1998 Jan-Feb;27(1-2):64-8, 70.
7
The use of inhaled formoterol in the treatment of asthma.吸入用福莫特罗在哮喘治疗中的应用。
Ann Allergy Asthma Immunol. 2006 Jul;97(1):24-33. doi: 10.1016/S1081-1206(10)61365-8.
8
Partial beta 2-agonists and their impartial assessment.部分β2激动剂及其客观评估。
Chest. 1996 Nov;110(5):1131-2. doi: 10.1378/chest.110.5.1131.
9
Evaluation of combination long-acting beta-2 agonists and inhaled glucocorticosteroids for treatment of asthma.长效β2受体激动剂与吸入性糖皮质激素联合治疗哮喘的评估。
Expert Opin Drug Metab Toxicol. 2009 Aug;5(8):933-40. doi: 10.1517/17425250903127226.
10
[Measurement of peak inspiratory flow with asthma: effect of inhaled beta2-stimulant].[哮喘患者吸气峰流速的测量：吸入β2激动剂的影响]
Nihon Kokyuki Gakkai Zasshi. 2005 Apr;43(4):216-20.
本文引用的文献
1
Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial.哮喘患者定期使用沙丁胺醇治疗：基因分型分层、随机、安慰剂对照交叉试验。
Lancet. 2004;364(9444):1505-12. doi: 10.1016/S0140-6736(04)17273-5.
2
Effect of inhaled fluticasone with and without salmeterol on airway inflammation in asthma.吸入氟替卡松联合或不联合沙美特罗对哮喘气道炎症的影响。
J Allergy Clin Immunol. 2003 Jul;112(1):72-8. doi: 10.1067/mai.2003.1518.
3
Is the increase in bronchial responsiveness or FEV1 shortly after cessation of beta2-agonists reflecting a real deterioration of the disease in allergic asthmatic patients? A comparison between short-acting and long-acting beta2-agonists.β2 激动剂停用后不久出现的支气管反应性增加或第一秒用力呼气容积（FEV1）增加，是否反映了过敏性哮喘患者疾病的真正恶化？短效与长效β2 激动剂的比较。
Respir Med. 2002 Mar;96(3):155-62. doi: 10.1053/rmed.2001.1243.
4
Low dose inhaled budesonide and formoterol in mild persistent asthma: the OPTIMA randomized trial.低剂量吸入布地奈德和福莫特罗治疗轻度持续性哮喘：OPTIMA随机试验
Am J Respir Crit Care Med. 2001 Oct 15;164(8 Pt 1):1392-7. doi: 10.1164/ajrccm.164.8.2104102.
5
Long-acting inhaled beta(2)-agonist therapy in asthma.哮喘的长效吸入型β₂受体激动剂治疗
Am J Respir Crit Care Med. 2001 Sep 15;164(6):923-32. doi: 10.1164/ajrccm.164.6.2010107.
6
Salmeterol powder provides significantly better benefit than montelukast in asthmatic patients receiving concomitant inhaled corticosteroid therapy.在接受吸入性糖皮质激素联合治疗的哮喘患者中，沙美特罗粉雾剂比孟鲁司特的疗效显著更好。
Chest. 2001 Aug;120(2):423-30. doi: 10.1378/chest.120.2.423.
7
Adding formoterol to budesonide in moderate asthma--health economic results from the FACET study.
Respir Med. 2001 Jun;95(6):505-12. doi: 10.1053/rmed.2001.1078.
8
Decreased bronchodilating effect of salbutamol in relieving methacholine induced moderate to severe bronchoconstriction during high dose treatment with long acting beta2 agonists.在长效β2激动剂高剂量治疗期间，沙丁胺醇缓解乙酰甲胆碱诱发的中度至重度支气管收缩的支气管扩张作用减弱。
Thorax. 2001 Jul;56(7):529-35. doi: 10.1136/thorax.56.7.529.
9
Reversing acute bronchoconstriction in asthma: the effect of bronchodilator tolerance after treatment with formoterol.逆转哮喘中的急性支气管收缩：福莫特罗治疗后支气管扩张剂耐受性的影响。
Eur Respir J. 2001 Mar;17(3):368-73. doi: 10.1183/09031936.01.17303680.
10
Compliance with inhaled glucocorticoids and concomitant use of long-acting beta2-agonists.吸入性糖皮质激素的依从性及长效β2受体激动剂的联合使用。
Respir Med. 2001 May;95(5):404-7. doi: 10.1053/rmed.2001.1060.
Zotero 插件