Nath Subrata D, Koutoubi Samer, Huffman Fatma G
Department of Dietetics and Nutrition, HLS 450, Stempel School of Public Health, Florida International University, Miami, FL 33199, USA.
J Natl Med Assoc. 2006 Jan;98(1):67-72.
Folic acid and vitamin B12 are of particular interest for their diverse biological functions and preventive roles in many prevalent chronic diseases. However, ethnic differences on the status of these vitamins have not been investigated among multiethnic adult college students.
A cross-sectional study (n = 177) was conducted to determine the dietary intakes and levels of serum concentrations of folate and vitamin B12 among triethnic college students-non-Hispanic white, Hispanic and non-Hispanic black. Dietary intake was assessed using a validated food frequency questionnaire, and serum was analyzed for folate and vitamin B12 using standardized methods.
Mean intakes of both vitamins without supplementation was higher (P < 0.05) among non-Hispanic white males than females, and non-Hispanic white and non-Hispanic black males and females. Non-Hispanic white females had a significantly lower mean dietary intake of vitamin B12 than the females of other ethnic groups (P < 0.01). There was a positive correlation between B12 intake and serum concentrations. More than 52% of the females did not meet the required folate intake of 400 microg/day.
The data suggest that there was no difference in overall mean intake of folate and vitamin B12 or serum concentrations in regard to gender or ethnicity. One-fourth of the female subjects failed to meet the recommended folate intake when supplement was excluded.
叶酸和维生素B12因其多样的生物学功能以及在许多常见慢性病中的预防作用而备受关注。然而,尚未在多民族成年大学生中研究这些维生素状况的种族差异。
开展了一项横断面研究(n = 177),以确定三个种族的大学生(非西班牙裔白人、西班牙裔和非西班牙裔黑人)的叶酸和维生素B12膳食摄入量及血清浓度水平。使用经过验证的食物频率问卷评估膳食摄入量,并采用标准化方法分析血清中的叶酸和维生素B12。
在不补充的情况下,非西班牙裔白人男性的这两种维生素平均摄入量高于女性,以及非西班牙裔白人和非西班牙裔黑人的男性和女性。非西班牙裔白人女性的维生素B12平均膳食摄入量显著低于其他种族的女性(P < 0.01)。B12摄入量与血清浓度之间存在正相关。超过52%的女性未达到每日400微克的叶酸摄入要求。
数据表明,叶酸和维生素B12的总体平均摄入量或血清浓度在性别或种族方面没有差异。排除补充剂后,四分之一的女性受试者未达到推荐的叶酸摄入量。