Reuse C, Fraisse T, Luzuy F, de Ziegler D
Endocrinologie gynécologique et médecine de la reproduction, Réseau romand de procréation assistée, HUG, Genève.
Rev Med Suisse. 2006 Feb 15;2(53):467, 469-70, 472 passim.
The WHI triggered a great debate on Menopausal Hormonal Therapy. We now know that HT should not be used in cardio-vascular prevention. Many studies have yet been published regarding it's influence on breast cancers. Risks should be modulated in respect with the type of treatment and the targeted population. Only recently menopaused women or women suffering from invalidating menopausal symptoms should benefit from HT. When an HT is needed, the authors recommend the use of trans-cutaneous estrogens combined with natural oral progesterone. Every HT should be prescribed individually, according to the patient's aspirations and expectations.
妇女健康倡议引发了关于更年期激素治疗的激烈辩论。我们现在知道，激素治疗不应用于心血管疾病预防。关于其对乳腺癌的影响，已有许多研究发表。风险应根据治疗类型和目标人群进行调整。只有最近绝经的女性或患有严重更年期症状的女性才应从激素治疗中获益。当需要进行激素治疗时，作者建议使用经皮雌激素联合天然口服孕激素。每种激素治疗都应根据患者的意愿和期望单独开处方。
