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Lymphedema.

作者信息

Rockson Stanley G

机构信息

Stanford Center for Lymphatic and Venous Disorders, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

出版信息

Curr Treat Options Cardiovasc Med. 2006 Apr;8(2):129-36. doi: 10.1007/s11936-006-0005-y.

DOI:10.1007/s11936-006-0005-y
PMID:16533487
Abstract

Aggressively applied decongestive measures (ie, manual lymphatic drainage, low-stretch bandaging, exercise, skin care, application of compressive elastic garments) are the mainstay of lymphatic therapy. Therapeutic regimens should differentiate between the sequential goals of acute volume reduction and maintenance of limb volume. Elastic garments should not be employed until maximal volume reduction has been attained through decongestive lymphatic techniques. It is my opinion that use of intermittent pneumatic compression devices can play an important adjunctive role to decongestive lymphatic therapy but should not be substituted for these techniques. At this time, I am not inclined to use pharmacologic therapy in these patients but anxiously await the results of studies that might demonstrate efficacy for molecular approaches. Surgical intervention is reserved for a small number of well-selected patients. Liposuction for volume reduction appears to be a very promising approach for specific patients.

摘要

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Addressing the unmet needs in lymphedema risk management.
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Transcriptome analysis and functional identification of adipose-derived mesenchymal stem cells in secondary lymphedema.
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Gland Surg. 2020 Apr;9(2):558-574. doi: 10.21037/gs.2020.02.09.
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Kir6.1-dependent K channels in lymphatic smooth muscle and vessel dysfunction in mice with Kir6.1 gain-of-function.Kir6.1 依赖性钾通道在淋巴管平滑肌中的作用及 Kir6.1 功能获得性突变小鼠血管功能障碍
J Physiol. 2020 Aug;598(15):3107-3127. doi: 10.1113/JP279612. Epub 2020 May 30.
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Topical bFGF Improves Secondary Lymphedema through Lymphangiogenesis in a Rat Tail Model.局部碱性成纤维细胞生长因子通过大鼠尾部模型中的淋巴管生成改善继发性淋巴水肿。
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Front Physiol. 2011 Dec 20;2:103. doi: 10.3389/fphys.2011.00103. eCollection 2011.
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