Wyckoff Myra H, Wyllie Jonathan
Department of Pediatrics, Division of Neonatal/Perinatal Medicine, University of Texas, Southwestern Medical Center, Dallas, TX 75290-9063, USA.
Clin Perinatol. 2006 Mar;33(1):153-60, ix. doi: 10.1016/j.clp.2005.11.013.
If the endotracheal route is to be used for administration of epinephrine, the limited available evidence suggests that the currently recommended dose of 0.01 mg/kg is likely to be too low to be effective. Given the paucity of high-quality clinical data regarding endotracheal epinephrine, the intravenous route should be used as soon as venous access is established. Given the complete lack of clinical data in newborns, endotracheal administration of naloxone is not recommended.
如果要通过气管内途径给予肾上腺素，有限的现有证据表明，目前推荐的0.01 mg/kg剂量可能过低而无效。鉴于关于气管内给予肾上腺素的高质量临床数据匮乏，一旦建立静脉通路，就应采用静脉途径。鉴于新生儿完全缺乏临床数据，不建议通过气管内给予纳洛酮。
