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韩国肥胖和超重所致的疾病负担。

Burden of disease attributable to obesity and overweight in Korea.

作者信息

Park J-H, Yoon S-J, Lee H, Jo H-S, Lee S-I, Kim Y, Kim Y-I, Shin Y

机构信息

Department of Health Policy and Management, College of Medicine, Seoul National University, Chongro-ku, Seoul, Korea.

出版信息

Int J Obes (Lond). 2006 Nov;30(11):1661-9. doi: 10.1038/sj.ijo.0803321. Epub 2006 Mar 14.

Abstract

OBJECTIVE

To estimate the burden of disease attributable to overweight and obesity using disability-adjusted life-year (DALY) in Korea.

RESEARCH METHODS

Firstly, overweight and obesity-related diseases and their relative risk (RR) were selected by the systematic review. Secondly, population-attributable fractions (PAFs) were computed by using the formula including RR and the prevalence of exposure (Pe) of overweight and obesity. Thirdly, DALYs of overweight and obesity-related diseases in Korea were estimated. Finally, the attributable burden (AB) of diseases due to overweight and obesity was calculated as the sum of the products from multiplying DALYs of overweight and obesity-related diseases by their PAFs.

RESULTS

The disease burden attributable to overweight was 827.1 person years (PYs) overall, 732.6 for men, 922.9 for women per 100,000 persons. The disease burden attributable to obesity was 260.0 PYs overall, 144.2 for men, 377.3 for women. Diabetes attributable to overweight and obesity accounts for highest burden among other diseases in both genders. The disease burden attributable to overweight was 3.2 times higher than that attributable to obesity.

CONCLUSION

Most proportion of disease burden attributable to high body mass index (BMI) occurred among those with only moderately raised levels such as overweight, not the extremes such as obesity. It suggests that population-based, public health intervention rather than high-risk group-focused strategies are more effective to reduce the burden of disease attributable to overweight and obesity in Korea.

摘要

目的

采用伤残调整生命年(DALY)评估韩国超重和肥胖所致的疾病负担。

研究方法

首先,通过系统评价选择超重和肥胖相关疾病及其相对危险度(RR)。其次,使用包含RR以及超重和肥胖暴露率(Pe)的公式计算人群归因分数(PAF)。第三,估算韩国超重和肥胖相关疾病的DALY。最后,将超重和肥胖相关疾病的DALY与其PAF相乘,计算这些乘积的总和,得出超重和肥胖所致疾病的归因负担(AB)。

结果

超重所致疾病负担总体为每10万人827.1人年(PYs),男性为732.6人年,女性为922.9人年。肥胖所致疾病负担总体为260.0人年,男性为144.2人年,女性为377.3人年。超重和肥胖所致糖尿病在两性的其他疾病中负担最高。超重所致疾病负担比肥胖所致疾病负担高3.2倍。

结论

高体重指数(BMI)所致疾病负担的大部分发生在超重等仅适度升高水平的人群中,而非肥胖等极端情况。这表明,在韩国,基于人群的公共卫生干预而非针对高危人群的策略,对于减轻超重和肥胖所致疾病负担更为有效。

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