Kuo Liang-Mou, Chou Hong-Shiue, Chan Kun-Ming, Yu Ming-Chin, Lee Wei-Chen
Department of General Surgery, Chang-Gung Memorial Hospital 5 and Medical School of Chang-Gung University, Fu-Hsing Street, Kwei-Shan, Taoyuan, Taiwan, China.
World J Gastroenterol. 2006 Feb 21;12(7):1157-9. doi: 10.3748/wjg.v12.i7.1157.
Primary liver liposarcoma is a rare disease. Because of its rarity, the knowledge of the clinical course, management, and prognosis of primary liver liposarcoma are all limited for clinicians. A 61-year-old female patient who suffered from a huge primary liposarcoma in the central portion of the liver had the clinical presentations of fever, nausea, vomiting, jaundice, and body weight loss. The huge tumor was resected successfully. However, the tumor recurred repeatedly and she had repeated hepatectomies to remove the tumor. The tumor became aggravating after repeated surgeries. Eventually, the patient had cervical spinal metastasis of liposarcoma and she survived for 26 months after liver liposarcoma was diagnosed. Although the tumor may become aggravating after repeated surgeries, repeated hepatectomies are still the best policy to achieve a long-term survival for the patients.
原发性肝脂肪肉瘤是一种罕见疾病。由于其罕见性,临床医生对原发性肝脂肪肉瘤的临床病程、治疗及预后的了解均有限。一名61岁女性患者,肝脏中央部患有巨大原发性脂肪肉瘤,临床表现为发热、恶心、呕吐、黄疸及体重减轻。巨大肿瘤被成功切除。然而,肿瘤反复复发,她多次接受肝切除术以切除肿瘤。反复手术后肿瘤病情加重。最终,该患者出现脂肪肉瘤颈椎转移,在肝脂肪肉瘤确诊后存活了26个月。尽管反复手术后肿瘤可能病情加重,但反复肝切除术仍是使患者获得长期生存的最佳策略。