体外灌注模型中下游动脉灌注参数对多普勒搏动指数和阻力指数的影响。
The influence of downstream arterial perfusion parameters on doppler pulsatility index and resistance index in an in-vitro perfusion model.
作者信息
Schmidt B, Ockert D, Deussen A, Schellong S
机构信息
Department of Angiology, Universitäts-Gefässzentrum Carl Gustav Carus, TU Dresden, Germany.
出版信息
Vasa. 2006 Feb;35(1):5-10. doi: 10.1024/0301-1526.35.1.5.
BACKGROUND
To investigate in vitro how downstream perfusion parameters influence pulsatility index (PI), resistance index (RI) and their constituting Doppler velocities.
MATERIALS AND METHODS
We analyzed the influence of resistance, compliance, reflection coefficient and input impedance on PI and RI in an in-vitro model of arterial flow.
RESULTS
The nominators of PI and RI were determined by resistance. The numerators were determined by compliance and by the reflection coefficient. There were close relationships of PI and RI with resistance under the condition of constant compliance, but not when compliance was variable.
CONCLUSION
PI and RI consist of velocity terms which are independently influenced by different parameters of impedance: compliance, reflection coefficient and resistance. These findings explain the contradictory results reported for the relationship between the indices and peripheral resistance in studies where compliance and reflection effects were not considered.
背景
在体外研究下游灌注参数如何影响搏动指数（PI）、阻力指数（RI）及其构成的多普勒速度。
材料与方法
我们在动脉血流的体外模型中分析了阻力、顺应性、反射系数和输入阻抗对PI和RI的影响。
结果
PI和RI的分子由阻力决定。分母由顺应性和反射系数决定。在顺应性恒定的情况下，PI和RI与阻力密切相关，但顺应性可变时则不然。
结论
PI和RI由速度项组成，这些速度项受到不同阻抗参数（顺应性、反射系数和阻力）的独立影响。这些发现解释了在未考虑顺应性和反射效应的研究中，这些指数与外周阻力之间关系所报告的矛盾结果。
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