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镶嵌植骨术:长期随访

Mosaicplasty: long-term follow-up.

作者信息

Szerb Imre, Hangody Laszlo, Duska Zsofia, Kaposi Novak Pal

机构信息

Orthopaedic and Trauma Department at Uzsoki Hospital, Budapest, Hungary.

出版信息

Bull Hosp Jt Dis. 2005;63(1-2):54-62.

Abstract

The successful treatment of chondral and osteochondral defects of the weightbearing surfaces is a challenge for orthopaedic surgeons. Autologous osteochondral transplantation is one method that can be used to create a hyaline or hyaline-like repair in the defect area. Ten years of clinical experience with autologous osteochondral mosaicplasty are described. Clinical scores, imaging techniques, arthroscopy, histological examination of biopsy samples, and cartilage stiffness measurements were used to evaluate the clinical outcomes and quality of the transplanted cartilage in a total of 831 patients who underwent mosaicplasty. According to our investigations, good-to-excellent results were achieved in 92% of the patients treated with femoral condylar implantations, in 87% of those treated with tibial resurfacing, in 79% of those treated with patellar and/or trochlear mosaicplasties, and in 94% of those treated with talarprocedures. Long-term donor-site disturbances, which were assessed using the Bandi score, showed that patients had 3% morbidity after mosaicplasty. Sixty-nine of 83 patients who were followed arthroscopically showed congruent gliding surfaces, histological evidence of the survival of the transplanted hyaline cartilage, and fibrocartilage filling of the donor sites. Four deep infections and 36 painful postoperative hemarthroses were experienced as complications arising from the surgical procedures. On the basis of both these promising results and also those of other similar studies, autologous osteochondral mosaicplasty would appears to be an alternative for the treatment of small and medium-sized focal chondral and osteochondral defects of the weightbearing surfaces of the knee and other weightbearing synovial joints.

摘要

负重面软骨和骨软骨缺损的成功治疗对骨科医生来说是一项挑战。自体骨软骨移植是一种可用于在缺损区域形成透明软骨或类似透明软骨修复的方法。本文描述了自体骨软骨镶嵌成形术的十年临床经验。使用临床评分、成像技术、关节镜检查、活检样本的组织学检查以及软骨硬度测量,对总共831例行镶嵌成形术患者的临床结果和移植软骨质量进行评估。根据我们的研究,股骨髁植入治疗的患者中92%取得了良好至优异的结果,胫骨表面置换治疗的患者中87%取得了良好至优异的结果,髌骨和/或滑车镶嵌成形术治疗的患者中79%取得了良好至优异的结果,距骨手术治疗的患者中94%取得了良好至优异的结果。使用班迪评分评估的长期供区并发症显示,镶嵌成形术后患者的发病率为3%。83例接受关节镜随访的患者中有69例显示滑动面一致,移植透明软骨存活的组织学证据,以及供区纤维软骨填充。手术过程中出现了4例深部感染和36例术后疼痛性关节积血等并发症。基于这些令人鼓舞 的结果以及其他类似研究的结果,自体骨软骨镶嵌成形术似乎是治疗膝关节和其他负重滑膜关节负重面中小型局灶性软骨和骨软骨缺损的一种替代方法。

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