Smith Blair H, Watt Graham C M, Campbell Harry, Sheikh Aziz
Department of General Practice and Primary Care, University of Aberdeen, Aberdeen.
Br J Gen Pract. 2006 Mar;56(524):214-21.
Large-scale, population-based studies of genetic epidemiology are under way or planned in several countries, including the UK. The results will have many implications for GPs and their patients. Primary care has much to contribute to this research, and basing genetic epidemiology studies in primary care will confer several advantages. These include enhanced public engagement, building on the personal relationships and trust that are at the core of primary care practice; methodological factors that will strengthen study design; and the potential of linkage of multiple datasets and between networks of research practices. Essential development work with primary care professionals and the public is, however, required for this to happen, and, if undertaken, this work will have the additional important benefit of increasing the uptake of new knowledge into general practice.
包括英国在内的几个国家正在开展或计划开展大规模的基于人群的遗传流行病学研究。这些结果将对全科医生及其患者产生诸多影响。初级保健可为这项研究做出很大贡献，而将遗传流行病学研究建立在初级保健基础上具有诸多优势。这些优势包括增强公众参与度，基于初级保健实践核心的人际关系和信任；加强研究设计的方法学因素；以及多个数据集和研究实践网络之间建立联系的潜力。然而，要实现这一点，需要与初级保健专业人员和公众开展必要的开发工作，并且如果开展这项工作，将带来额外的重要好处，即增加新知识在全科医疗中的应用。
