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[肿瘤学中的遗传流行病学]

[Genetic epidemiology in oncology].

作者信息

Bonilla Velasco F

机构信息

Servicio de Oncología Médica, Clínica Puerta de Hierro, Madrid.

出版信息

An Med Interna. 1994 Dec;11(12):610-2.

PMID:7734671
Abstract

Genetic Epidemiology is a discipline which studies the incidence of diseases among the population, trying to quantify at the same time the individual risk of developing them. In Oncology, it is based on the analysis of the patients genealogies and on the study of the polymorphisms in their DNA with specific markers. Its operation requires a laboratory duly equipped with the techniques of Molecular Biology, a section responsible of data collection regarding patients and relatives and another area for the computer processing of data and results. Its funding shall be through public agencies, but the private companies related with this field must be aware of the need to participate in these projects.

摘要

遗传流行病学是一门研究人群中疾病发病率的学科,同时试图量化个体患这些疾病的风险。在肿瘤学中,它基于对患者家谱的分析以及对其DNA中特定标记多态性的研究。其运作需要一个配备了分子生物学技术的实验室、一个负责收集患者及其亲属数据的部门以及另一个用于数据和结果计算机处理的区域。其资金应来自公共机构,但与该领域相关的私营公司必须意识到参与这些项目的必要性。

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