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1994 - 1998年科罗拉多州创伤性脑损伤后死亡率的性别差异

Sex differences in mortality after traumatic brain injury, Colorado 1994-1998.

作者信息

Gujral Indira B, Stallones Lorann, Gabella Barbara A, Keefe Thomas J, Chen Peter

机构信息

Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, 80523-1676, USA.

出版信息

Brain Inj. 2006 Mar;20(3):283-91. doi: 10.1080/02699050500488058.

DOI:10.1080/02699050500488058
PMID:16537270
Abstract

PRIMARY OBJECTIVE

The purpose of this study was to assess the relationship between sex and traumatic brain injury (TBI) mortality.

METHODS AND PROCEDURES

A total of 20,465 persons with TBI were identified from a Colorado population-based surveillance system for 1994-1998. Case fatality ratios were calculated to identify sex differences for selected risk factors. Unconditional logistic regression was used to determine the relationship between TBI mortality and sex controlling for risk factors.

MAIN OUTCOMES AND RESULTS

Adjusting for age, race, metropolitan residence and penetrating injury, the estimated odds of TBI mortality for males compared to females was 1.21 (95% CI 1.10, 1.34) for pre-hospital fatalities and 1.19 (95% CI 1.05, 1.37) for hospital fatalities.

CONCLUSION

Results indicate differences in TBI mortality comparing males and females. Future studies are warranted to identify if behaviour and physiological responses are associated with TBI outcomes among males and females.

摘要

主要目标

本研究的目的是评估性别与创伤性脑损伤(TBI)死亡率之间的关系。

方法与步骤

从科罗拉多州基于人群的1994 - 1998年监测系统中识别出总共20465例创伤性脑损伤患者。计算病例死亡率以确定选定风险因素的性别差异。使用无条件逻辑回归来确定创伤性脑损伤死亡率与控制风险因素后的性别之间的关系。

主要结果

在调整年龄、种族、大都市居住情况和穿透性损伤后,男性创伤性脑损伤院前死亡率与女性相比的估计比值比为1.21(95%可信区间1.10, 1.34),院内死亡率为1.19(95%可信区间1.05, 1.37)。

结论

结果表明男性和女性在创伤性脑损伤死亡率方面存在差异。有必要进行进一步研究以确定行为和生理反应是否与男性和女性的创伤性脑损伤结果相关。

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