Steele Natalie P, Myssiorek David
Department of Otolaryngology, Albert Einstein College of Medicine, Bronx, New York 11040, USA.
Laryngoscope. 2006 Mar;116(3):494-6. doi: 10.1097/01.mlg.0000194637.83266.a3.
West Nile virus has recently become a public health concern in the United States, after an outbreak in New York City in 1999. It is a mosquito-borne virus that causes a spectrum of disease from flu-like symptoms to encephalopathy, muscle weakness, and, in some cases, death.
Case Report.
A patient infected with West Nile virus presented with progressive muscle weakness, and later developed bilateral vocal fold paresis. His clinical presentation, physical and laboratory examination findings, and course of illness will be discussed.
After a prolonged hospital stay, and presumptive treatment for Guillain-Barré, repeat CSF analysis revealed infection with the West Nile virus. The patient developed bilateral vocal fold paralysis during his hospital course. At long-term follow-up, the patient's left vocal fold paralysis persisted, while the right vocal fold paralysis had resolved.
Although several viruses have been associated with recurrent laryngeal nerve injury, this is the first report of West Nile virus induced vocal fold paralysis.
1999年纽约市爆发疫情后，西尼罗河病毒最近在美国成为一个公共卫生问题。它是一种由蚊子传播的病毒，可引发一系列疾病，从类似流感的症状到脑病、肌肉无力，在某些情况下还会导致死亡。
病例报告。
一名感染西尼罗河病毒的患者出现进行性肌肉无力，随后发展为双侧声带麻痹。将讨论其临床表现、体格检查和实验室检查结果以及病程。
经过长时间住院，并对格林-巴利综合征进行推定治疗后，重复脑脊液分析显示感染了西尼罗河病毒。患者在住院期间发展为双侧声带麻痹。长期随访时，患者左侧声带麻痹持续存在，而右侧声带麻痹已缓解。
虽然有几种病毒与喉返神经损伤有关，但这是西尼罗河病毒诱发声带麻痹的首例报告。
