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在接受冠状动脉旁路移植术(CABG)和主动脉瓣手术的患者中进行永久性心房颤动消融手术,其效果至少与二尖瓣疾病患者相同。

Permanent atrial fibrillation ablation surgery in CABG and aortic valve patients is at least as effective as in mitral valve disease.

作者信息

Geidel S, Ostermeyer J, Lass M, Geisler M, Kotetishvili N, Aslan H, Boczor S, Kuck K-H

机构信息

Abteilung für Herzchirurgie, Allgemeines Krankenhaus St. Georg, Hamburg, Germany.

出版信息

Thorac Cardiovasc Surg. 2006 Mar;54(2):91-5. doi: 10.1055/s-2005-872860.

Abstract

BACKGROUND

Data on combined permanent atrial fibrillation (pAF) surgery and coronary artery bypass grafting (CABG) and/or aortic valve replacement (AVR) are scarce, and the mid- and long-term effects on survival and cardiac rhythm are unknown.

MATERIAL AND METHODS

In a prospective analysis 125 patients (Group I: CABG and/or AVR, n = 50; Group II: mitral valve [MV] surgery, n = 75) with pAF (> or = 6 months) underwent either concomitant monopolar (Group I: n = 20; Group II: n = 75) or bipolar (Group I: n = 30) radiofrequency (RF) ablation procedures. Group I patients had a significantly smaller left atrial (LA) size than Group II patients (LA-diameter: 47.7 +/- 4.6 vs. 58.2 +/- 6.1 mm; p < 0.01). Regular follow-up was performed from 3 to 36 months after surgery to assess survival, NYHA-class, and conversion rate to stable sinus rhythm (SR).

RESULTS

Early mortality (< 30 days) of Group I patients was 0% (Group II: 2.7%), cumulative survival at long-term follow-up was 0.95 vs. 0.82 (p = 0.31) and NYHA-class improved significantly in both groups, particularly in cases with stable SR. At follow-up 80% of Group I patients had SR (Group II: 70%). In Group I patients the bipolar approach was associated with significantly shorter ablation procedure times compared to the monopolar procedure (12.1 +/- 3.4 vs. 18.9 +/- 1.6 min; p < 0.05).

CONCLUSIONS

Concomitant pAF ablation surgery in CABG and/or AVR is safe and at least as effective as in MV surgery, presumably because severe LA enlargement is exceptionally rare in this group.

摘要

背景

关于永久性心房颤动(pAF)手术与冠状动脉旁路移植术(CABG)和/或主动脉瓣置换术(AVR)联合应用的数据稀少,其对生存和心律的中长期影响尚不清楚。

材料与方法

在一项前瞻性分析中,125例患有pAF(≥6个月)的患者(I组:CABG和/或AVR,n = 50;II组:二尖瓣[MV]手术,n = 75)接受了单极(I组:n = 20;II组:n = 75)或双极(I组:n = 30)射频(RF)消融术。I组患者的左心房(LA)大小明显小于II组患者(LA直径:47.7±4.6 vs. 58.2±6.1 mm;p < 0.01)。术后3至36个月进行定期随访,以评估生存率、纽约心脏协会(NYHA)心功能分级以及转为稳定窦性心律(SR)的转化率。

结果

I组患者的早期死亡率(<30天)为0%(II组:2.7%),长期随访时的累积生存率为0.95 vs. 0.82(p = 0.3),两组的NYHA心功能分级均显著改善,尤其是在SR稳定的病例中。随访时,I组80%的患者为SR(II组:70%)。在I组患者中,与单极手术相比,双极手术方法的消融手术时间明显更短(12.1±3.4 vs. 18.9±1.6分钟;p < 0.05)。

结论

CABG和/或AVR术中联合pAF消融手术是安全的,且至少与MV手术一样有效,可能是因为该组中严重LA扩大极为罕见。

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