Geidel Stephan, Lass Michael, Ostermeyer Jörg
Hanseatisches Herzzentrum, Abteilung für Herzchirurgie, Asklepios Klinik St Georg, Lohmühlenstrasse 5, 20099 Hamburg, Germany.
Interact Cardiovasc Thorac Surg. 2008 Oct;7(5):777-80. doi: 10.1510/icvts.2008.179622. Epub 2008 Jul 2.
This study analyses the 5-year results of permanent atrial fibrillation (pAF) bipolar radiofrequency (RF) ablation surgery concomitant to coronary artery bypass grafting (CABG) and/or aortic valve (AV) surgery. Eighty-five patients with pAF (0.5-30 years) underwent bipolar RF ablation procedure concomitant to CABG/AV surgery. All patients were restudied to assess survival, conversion rate to stable sinus rhythm (SR) and New York Heart Association (NYHA) class at 8+/-1 days and at 3+/-1 and 32+/-15 months after surgery. Survival at time of re-examination was 100%, 98% and 96%, respectively (three non-cardiac deaths), SR could be documented in 61%, 74% and 78% of patients. Long-term AF before surgery and larger size of the left atrium (LA) were predictive for postoperative AF return (P=0.005, P=0.03); 88% of patients with small preoperative LA-size (<50 mm) and 85% with pAF-duration time <5 years had stable SR at late follow-up. Cardiac rhythm at three months was predictive for long-term rhythm-prognosis (P<0.0001). NYHA-class improved significantly after surgery (P<0.0005), particularly when SR was achieved (P=0.046). Permanent AF bipolar RF ablation surgery revealed excellent results in AV/CABG patients. It could be demonstrated that established SR remained stable over time. Preoperative pAF-duration time and LA-size are useful variables to predict the success rate of ablation.
本研究分析了永久性心房颤动(pAF)双极射频(RF)消融手术与冠状动脉旁路移植术(CABG)和/或主动脉瓣(AV)手术同时进行的5年结果。85例pAF患者(0.5 - 30岁)在CABG/AV手术同时接受了双极RF消融手术。所有患者在术后8±1天、3±1个月和32±15个月时再次接受评估,以评估生存率、转为稳定窦性心律(SR)的转化率以及纽约心脏协会(NYHA)心功能分级。复查时的生存率分别为100%、98%和96%(3例非心脏死亡),61%、74%和78%的患者可记录到SR。术前长期房颤和左心房(LA)较大是术后房颤复发的预测因素(P = 0.005,P = 0.03);术前LA尺寸小(<50 mm)的患者中88%以及pAF持续时间<5年的患者中85%在晚期随访时具有稳定的SR。术后三个月的心律是长期心律预后的预测因素(P<0.0001)。术后NYHA分级显著改善(P<0.0005),尤其是在实现SR时(P = 0.046)。永久性房颤双极RF消融手术在AV/CABG患者中显示出优异的结果。可以证明,已建立的SR随时间保持稳定。术前pAF持续时间和LA尺寸是预测消融成功率的有用变量。