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双极射频消融治疗冠状动脉旁路移植术和主动脉瓣手术合并永久性心房颤动的5年临床经验。

A 5-year clinical experience with bipolar radiofrequency ablation for permanent atrial fibrillation concomitant to coronary artery bypass grafting and aortic valve surgery.

作者信息

Geidel Stephan, Lass Michael, Ostermeyer Jörg

机构信息

Hanseatisches Herzzentrum, Abteilung für Herzchirurgie, Asklepios Klinik St Georg, Lohmühlenstrasse 5, 20099 Hamburg, Germany.

出版信息

Interact Cardiovasc Thorac Surg. 2008 Oct;7(5):777-80. doi: 10.1510/icvts.2008.179622. Epub 2008 Jul 2.

DOI:10.1510/icvts.2008.179622
PMID:18596056
Abstract

This study analyses the 5-year results of permanent atrial fibrillation (pAF) bipolar radiofrequency (RF) ablation surgery concomitant to coronary artery bypass grafting (CABG) and/or aortic valve (AV) surgery. Eighty-five patients with pAF (0.5-30 years) underwent bipolar RF ablation procedure concomitant to CABG/AV surgery. All patients were restudied to assess survival, conversion rate to stable sinus rhythm (SR) and New York Heart Association (NYHA) class at 8+/-1 days and at 3+/-1 and 32+/-15 months after surgery. Survival at time of re-examination was 100%, 98% and 96%, respectively (three non-cardiac deaths), SR could be documented in 61%, 74% and 78% of patients. Long-term AF before surgery and larger size of the left atrium (LA) were predictive for postoperative AF return (P=0.005, P=0.03); 88% of patients with small preoperative LA-size (<50 mm) and 85% with pAF-duration time <5 years had stable SR at late follow-up. Cardiac rhythm at three months was predictive for long-term rhythm-prognosis (P<0.0001). NYHA-class improved significantly after surgery (P<0.0005), particularly when SR was achieved (P=0.046). Permanent AF bipolar RF ablation surgery revealed excellent results in AV/CABG patients. It could be demonstrated that established SR remained stable over time. Preoperative pAF-duration time and LA-size are useful variables to predict the success rate of ablation.

摘要

本研究分析了永久性心房颤动(pAF)双极射频(RF)消融手术与冠状动脉旁路移植术(CABG)和/或主动脉瓣(AV)手术同时进行的5年结果。85例pAF患者(0.5 - 30岁)在CABG/AV手术同时接受了双极RF消融手术。所有患者在术后8±1天、3±1个月和32±15个月时再次接受评估,以评估生存率、转为稳定窦性心律(SR)的转化率以及纽约心脏协会(NYHA)心功能分级。复查时的生存率分别为100%、98%和96%(3例非心脏死亡),61%、74%和78%的患者可记录到SR。术前长期房颤和左心房(LA)较大是术后房颤复发的预测因素(P = 0.005,P = 0.03);术前LA尺寸小(<50 mm)的患者中88%以及pAF持续时间<5年的患者中85%在晚期随访时具有稳定的SR。术后三个月的心律是长期心律预后的预测因素(P<0.0001)。术后NYHA分级显著改善(P<0.0005),尤其是在实现SR时(P = 0.046)。永久性房颤双极RF消融手术在AV/CABG患者中显示出优异的结果。可以证明,已建立的SR随时间保持稳定。术前pAF持续时间和LA尺寸是预测消融成功率的有用变量。

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