Tzanova S, Ivanova Z, Velinova S
Department of Operative Dentistry and Endodontics, Faculty of Dentistry, Medical University-Plovdiv, Bulgaria.
Folia Med (Plovdiv). 2005;47(2):65-9.
To evaluate the desensitizing effect of a Bulgarian-made dentifrice containing 5% potassium nitrate in a double-blind experiment.
The study included 40 clinically healthy individuals aged 23 to 60 years, who complained of increased sensitivity to thermal, chemical and mechanical stimuli in 462 teeth. The recruited patients were allocated into two groups: 20 patients were treated with the Sensi I dentifrice, and the other 20--the Sensi II dentifrice. The outcome of treatment was evaluated by any alteration in pain sensitiveness in response to different stimuli and changes in the threshold of electrical excitability.
The Sensi I toothpaste (containing 5% potassium nitrate) was found to have a better desensitizing effect than the Sensi II placebo toothpaste (P < 0.01). The Sensi I dentifrice caused a rise in the threshold of electrical excitability of sensitive teeth with clinically intact enamel (P < 0.01), teeth with erosions (P < 0.05) and teeth with exposed root surfaces (P < 0.001).
The Sensi toothpaste, containing 5% potassium nitrate, demonstrated a pronounced anesthetizing effect; it can be used successfully for treatment of dentinal hypersensitivity of teeth with clinically intact enamel, erosions and exposed root surfaces due to gingival recessions.
在一项双盲实验中评估一款含5%硝酸钾的保加利亚产牙膏的脱敏效果。
该研究纳入了40名年龄在23至60岁之间的临床健康个体,他们抱怨462颗牙齿对热、化学和机械刺激的敏感度增加。招募的患者被分为两组:20名患者使用Sensi I牙膏治疗,另外20名使用Sensi II牙膏。通过对不同刺激的疼痛敏感度的任何改变以及电兴奋性阈值的变化来评估治疗结果。
发现Sensi I牙膏(含5%硝酸钾)比Sensi II安慰剂牙膏具有更好的脱敏效果(P < 0.01)。Sensi I牙膏使临床牙釉质完整的敏感牙齿(P < 0.01)、有侵蚀的牙齿(P < 0.05)和牙根面暴露的牙齿(P < 0.001)的电兴奋性阈值升高。
含5%硝酸钾的Sensi牙膏显示出显著的麻醉效果;它可成功用于治疗临床牙釉质完整、有侵蚀以及因牙龈退缩导致牙根面暴露的牙齿的牙本质过敏。