Rayner Julian C
Division of Geographic Medicine, Department of Medicine, University of Alabama at Birmingham, 845 19th St South, Birmingham, AL 35294, USA.
Trends Parasitol. 2006 May;22(5):189-92. doi: 10.1016/j.pt.2006.02.013. Epub 2006 Mar 20.
A new study has combined video microscopy with fluorescent labeling of host and parasite membranes to follow Plasmodium falciparum merozoites as they exit their host erythrocyte. The result has yielded some arresting images, which make compelling viewing irrespective of whether or not you have an interest in cell motility in general or P. falciparum erythrocyte exit in particular. Moreover, this work injects important new insights into the long-running debate about the biological mechanisms that underpin merozoite release.
一项新研究将视频显微镜技术与宿主和寄生虫膜的荧光标记相结合,以追踪恶性疟原虫裂殖子离开其宿主红细胞的过程。研究结果产生了一些引人注目的图像,无论你是否对一般的细胞运动性,特别是恶性疟原虫从红细胞中逸出感兴趣,这些图像都极具观赏性。此外,这项工作为关于裂殖子释放背后生物学机制的长期争论注入了重要的新见解。