Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, UK.
Curr Biol. 2011 May 10;21(9):R314-6. doi: 10.1016/j.cub.2011.03.066.
A recent study reveals that the intraerythrocytic asexual reproduction cycle of Plasmodium falciparum ends with the ruptured erythrocyte membrane curling outwards, buckling, everting and vesiculating. Analogy with the sequence seen during spontaneous inside-out vesiculation of erythrocyte membranes suggests that the parasite co-opts pre-existing cytoskeletal conformations to facilitate terminal merozoite dispersal.
最近的一项研究表明，恶性疟原虫的红细胞内无性生殖周期以破裂的红细胞膜向外卷曲、弯曲、外翻和起泡为终点。与红细胞膜自发内面向外翻泡过程中观察到的序列相似，表明寄生虫利用预先存在的细胞骨架构象来促进终末裂殖体的分散。
