Pruniéras M, Grupper C, Durepaire R, Régnier M
Nouv Presse Med. 1975 Mar 15;4(11):787-9.
Peripheral blood lymphocytes from one hundred patients with skin disorders have been examined under the electron microscope. The bloods of 20 donors were used as controls. One observed: Branched Tubular Structures (so-called Lupus type inclusions) in 8 cases (4 systemic Lupus Erythematosus out of 15; I mixed connective tissue disorder; 3 cutaneous lymphomas). As regards Lupus, these findings are in agreement with those already reported in the literature. However, the presence of such inclusions in Lymphomas calls attention once again on the fact that the lymphocyte appears like a possible common denominator to both autoimmune diseases and lymphomas; Intented or cerebriform nuclei in 12 cases, all lymphomas, including 8 cases of Sezary Syndrome out of 8 and 4 Mycosis Fungoïdes out of 12; Lamellar type inclusions, similar to those described by Hovig, in 13 cases (connective tissue disease 1, lymphomas 2, psoriasis 4, miscellaneous 4, healthy controls 2). Their meaning is unclear; they may be artifacts.
对100例皮肤病患者的外周血淋巴细胞进行了电子显微镜检查。以20名供血者的血液作为对照。观察到：8例出现分支管状结构（所谓狼疮样包涵体）（15例系统性红斑狼疮中有4例；1例混合性结缔组织病；3例皮肤淋巴瘤）。关于狼疮，这些发现与文献中已报道的一致。然而，淋巴瘤中出现这种包涵体再次提醒人们注意，淋巴细胞似乎是自身免疫性疾病和淋巴瘤的一个可能的共同特征；12例出现异形或脑回状核，均为淋巴瘤，包括8例蕈样肉芽肿综合征中的8例和12例蕈样霉菌病中的4例；13例出现类似于霍维格所描述的板层样包涵体（结缔组织病1例，淋巴瘤2例，银屑病4例，其他4例，健康对照2例）。其意义尚不清楚；可能是人为现象。
