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[关于骨骼负荷过重疾病的病因和发病机制的当前理论]

[Current theories on the etiology and pathogenesis of overload diseases of bones].

作者信息

Evdokimov A E

出版信息

Vestn Khir Im I I Grek. 1991 Mar;146(3):27-31.

PMID:1654629
Abstract

The state of the neuroendocrine system and protein metabolism was studied in 307 young servicemen having overload disease of bones. It was established that in 92.9% of the patients the level of growth hormone--somatotropic hormone, was considerably reduced, production of important for osteogenesis thyroid hormones was disturbed and dissociation of protein fractions was detected which is thought by the author to be the primary cause of the overload disease of the bones.

摘要

对307名患有骨骼负荷过重疾病的年轻军人的神经内分泌系统状态和蛋白质代谢进行了研究。结果发现,92.9%的患者生长激素——促生长激素水平显著降低,对骨生成至关重要的甲状腺激素分泌紊乱,且检测到蛋白质组分解离,作者认为这是骨骼负荷过重疾病的主要原因。

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