外周血雌二醇、孕酮和睾酮水平与肠易激综合征的关联
[Association of peripheral blood estradiol, progesterone and testosterone levels with irritable bowel syndrome].
作者信息
Cui Nan, Wu Bao-ping, Wu Sai-zhu
机构信息
Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
出版信息
Nan Fang Yi Ke Da Xue Xue Bao. 2006 Mar;26(3):367-8.
OBJECTIVE
To investigate the relation of peripheral blood estradiol, progesterone and testosterone levels with irritable bowel syndrome (IBS).
METHODS
Forty-eight patients with IBS identified according to Rome II diagnostic criteria and 30 healthy subjects as controls were analyzed for peripheral blood sex hormone levels by radioimmunoassay and corresponding software.
RESULTS
In male patients with IBS, blood testosterone level was significantly lower than that of the control group (P<0.05), but blood estradiol and progesterone showed no significant differences between the two groups (P>0.05). In the female patients, blood estradiol level was significantly lower than that of the control group (P<0.05), whereas blood progesterone and testosterone levels had no significant differences between the two groups (P>0.05).
CONCLUSION
Peripheral blood testosterone level in male IBS patients and estradiol level in female patients are lower than those of healthy subjects, suggesting that IBS might be associated with blood sex hormone disorder.
目的
探讨外周血雌二醇、孕酮和睾酮水平与肠易激综合征（IBS）的关系。
方法
采用放射免疫分析法及相应软件，对48例根据罗马II诊断标准确诊的IBS患者和30例健康对照者的外周血性激素水平进行分析。
结果
男性IBS患者血睾酮水平显著低于对照组（P<0.05），但两组血雌二醇和孕酮水平无显著差异（P>0.05）。女性患者血雌二醇水平显著低于对照组（P<0.05），而两组血孕酮和睾酮水平无显著差异（P>0.05）。
结论
男性IBS患者外周血睾酮水平及女性患者外周血雌二醇水平低于健康受试者，提示IBS可能与血性激素紊乱有关。
Zotero 插件