Prescrire Int. 2006 Feb;15(81):19.
(1) Nicorandil, a vasodilator marketed for symptomatic relief of angina pectoris, is known to cause mouth ulcers, which can sometimes be very large. (2) Cases of anal ulceration have also been reported, associated with pain and, sometimes, a bloody discharge. These anal ulcerations heal very slowly (several weeks) after nicorandil withdrawal.
（1）尼可地尔是一种用于缓解心绞痛症状的血管扩张剂，已知会导致口腔溃疡，有时溃疡会非常大。（2）也有肛门溃疡的病例报告，伴有疼痛，有时还有血性分泌物。停用尼可地尔后，这些肛门溃疡愈合非常缓慢（数周）。
