尼可地尔相关性肛门溃疡
Nicorandil related anal ulcer.
作者信息
Al-Hilli Z, Pritchard R, Roche-Nagle G, Deasy J, McNamara D A
机构信息
Dept of Colorectal Surgery, Beaumont Hospital, Dublin 9.
出版信息
Ir J Med Sci. 2006 Jul-Sep;175(3):62-3. doi: 10.1007/BF03169175.
BACKGROUND
Anal ulceration is uncommon. Patients are typically referred because of severe anal pain, bleeding, discharge, and ulceration. It is important to exclude anal carcinoma, and to consider more unusual causes.
METHODS
A 74-year-old lady presented with severe anal pain and ulceration. This was subsequently noted to be related to nicorandil, a potassium channel activator used in the treatment of angina. Discontinuation of nicorandil and faecal diversion allowed symptom relief and ulcer healing.
CONCLUSION
Knowledge of the association between nicorandil and anal ulceration is essential in order to appropriately diagnose and manage this condition.
背景
肛门溃疡并不常见。患者通常因严重的肛门疼痛、出血、分泌物及溃疡而前来就诊。排除肛门癌并考虑更罕见的病因很重要。
方法
一名74岁女性因严重的肛门疼痛和溃疡前来就诊。随后发现这与尼可地尔有关，尼可地尔是一种用于治疗心绞痛的钾通道激活剂。停用尼可地尔并进行粪便转流后症状缓解，溃疡愈合。
结论
了解尼可地尔与肛门溃疡之间的关联对于正确诊断和处理这种情况至关重要。
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