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痹祺胶囊治疗类风湿关节炎的临床观察

[Clinical observation on treatment of rheumatoid arthritis with biqi capsule].

作者信息

Liu Wei, Zhang Lei, Xu Zhao

机构信息

Rheumatic Department, the First Hospital Affiliated to Tianjin College of TCM, Tianjin 300193.

出版信息

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2006 Feb;26(2):157-9.

PMID:16548360
Abstract

OBJECTIVE

To study the indication and clinical efficacy of Biqi capsule (BC) in treating patients with rheumatoid arthritis (RA).

METHODS

One hundred and forty-two RA patients were randomly divided into the BC treated group and the control group treated with nimesulide tablet (NT). There were 36 patients with dampness-heat blockage syndrome type and 35 patients with Qi deficiency and blood stasis syndrome type in each group. The treatment course lasted for 8 weeks.

RESULTS

The total effective rate in the BC group was 66.2% (47 cases), while that in the control group was 60.6% (43 cases). The total effective rate in the patients with Qi deficiency and blood stasis syndrome type in the BC group was 91.4%, superior to that with dampness-heat blockage type (41.7%). Only one patient showed mild adverse reaction in the BC group.

CONCLUSION

BC is a kind of safe and effective herble medicine for treatment of RA, especially for those of Qi deficiency and blood stasis syndrome type.

摘要

目的

研究痹祺胶囊(BC)治疗类风湿关节炎(RA)患者的适应证及临床疗效。

方法

142例RA患者随机分为BC治疗组和尼美舒利片(NT)治疗的对照组。每组中湿热痹阻证型患者36例,气血亏虚证型患者35例。疗程持续8周。

结果

BC组总有效率为66.2%(47例),而对照组为60.6%(43例)。BC组中气血亏虚证型患者的总有效率为91.4%,优于湿热痹阻型(41.7%)。BC组仅1例患者出现轻度不良反应。

结论

BC是治疗RA的一种安全有效的草药,尤其适用于气血亏虚证型患者。

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引用本文的文献

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Traditional Chinese medicine Biqi capsule compared with leflunomide in combination with methotrexate in patients with rheumatoid arthritis: a randomized controlled trial.中药痹祺胶囊与来氟米特联合甲氨蝶呤治疗类风湿关节炎的随机对照试验
Chin Med. 2020 Apr 23;15:36. doi: 10.1186/s13020-020-00319-9. eCollection 2020.
2
Traditional Chinese medicine formula Bi-Qi capsule alleviates rheumatoid arthritis-induced inflammation, synovial hyperplasia, and cartilage destruction in rats.中药配方芪七胶囊减轻大鼠类风湿性关节炎引起的炎症、滑膜增生和软骨破坏。
Arthritis Res Ther. 2018 Mar 14;20(1):43. doi: 10.1186/s13075-018-1547-6.
3
Systematic review of the methodological quality of controlled trials evaluating Chinese herbal medicine in patients with rheumatoid arthritis.
对评估类风湿关节炎患者使用中药的对照试验方法学质量的系统评价。
BMJ Open. 2017 Mar 1;7(3):e013242. doi: 10.1136/bmjopen-2016-013242.