Choo Sung Wook, Shin Sung Wook, Do Young Soo, Liu Wei Chiang, Park Kwang Bo, Sung Yon Mi, Choo In Wook
Department of Radiology and Center for Imaging Saience, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Korean J Radiol. 2006 Jan-Mar;7(1):41-9. doi: 10.3348/kjr.2006.7.1.41.
We wanted to evaluate the therapeutic efficacy of the percutaneous balloon dilatation and large profile catheter maintenance method for the management of patients with anastomotic biliary strictures following liver transplant.
From May 1999 to June 2003, 12 patients with symptomatic benign biliary stricture complicated by liver transplantation were treated with the percutaneous balloon dilatation and large profile catheter maintenance method (1-6 months). The patients were eight males and four females, and their ages ranged from 20 to 62 years (mean age: 44 years). Ten patients underwent living donor liver transplantation and two underwent cadaveric liver transplantation. Postoperative biliary strictures occurred from two to 21 months (mean age: 18 months) after liver transplantation.
The initial technical success rate was 92%. Patency of the bile duct was preserved for eight to 40 months (mean period: 19 months) in 10 of 12 (84%) patients. When reviewing two patients (17%), secondary balloon dilatations were needed for treating the delayed recurrence of biliary stricture. In one patient, no recurrent stenosis was seen during the further 10 months follow-up after secondary balloon dilatation. Another patient did not response to secondary balloon dilatation, and he was treated by surgery. Eleven of 12 patients (92%) showed good biliary patency for 8-40 months (mean period: 19 months) of follow-up.
The percutaneous balloon dilatation and large profile catheter maintenance method is an effective therapeutic alternative for the treatment of most biliary strictures that complicate liver transplantation. It has a high success rate and it should be considered before surgery.
我们旨在评估经皮球囊扩张及大口径导管维持法在肝移植术后吻合口胆管狭窄患者治疗中的疗效。
1999年5月至2003年6月,12例肝移植术后出现症状性良性胆管狭窄的患者接受了经皮球囊扩张及大口径导管维持法治疗(1 - 6个月)。患者中男性8例,女性4例,年龄范围为20至62岁(平均年龄:44岁)。10例患者接受活体供肝肝移植,2例接受尸体供肝肝移植。术后胆管狭窄发生于肝移植后2至21个月(平均时间:18个月)。
初始技术成功率为92%。12例患者中有10例(84%)胆管通畅维持了8至40个月(平均时间:19个月)。回顾2例患者(17%),因胆管狭窄延迟复发需要进行二次球囊扩张。1例患者在二次球囊扩张后的进一步10个月随访中未见复发狭窄。另1例患者对二次球囊扩张无反应,接受了手术治疗。12例患者中有11例(92%)在8至40个月(平均时间:19个月)的随访中显示胆管通畅良好。
经皮球囊扩张及大口径导管维持法是治疗大多数肝移植术后并发胆管狭窄的有效治疗选择。其成功率高,在手术前应予以考虑。