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经皮气囊扩张联合经皮肝穿刺胆管置管引流术治疗21例良性胆管狭窄且内镜治疗困难患者的临床观察

[A clinical observation of percutaneous balloon dilation and maintenance percutaneous transhepatic cholangial catheter drainage for treatment of 21 patients with benign biliary strictures and difficult endoscopy].

作者信息

Pan Jie, Shi Hai-feng, Li Xiao-guang, Zhang Xiao-bo, Liu Wei, Jin Zheng-yu, Hong Tao, Yang Ai-ming, Yang Ning

机构信息

Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

出版信息

Zhonghua Nei Ke Za Zhi. 2012 Jun;51(6):433-6.

Abstract

OBJECTIVE

To investigate the value of percutaneous balloon dilation and percutaneous transhepatic cholangial drainage (PTCD) catheter maintenance in the treatment of benign biliary strictures.

METHODS

The clinical data of 21 patients with benign biliary strictures at Peking Union Medical College Hospital from June 2005 to June 2011 were retrospectively studied, in which 12 patients in severe stricture (stenosis > 70%) were treated with percutaneous balloon dilation and PTCD catheter placed across the stricture, while another 9 patients in median stricture (stenosis < 70%) were only treated with PTCD catheter maintenance.

RESULTS

Of the 12 patients underwent balloon dilation and 6 - 12 months (median: 9 months) of PTCD catheter placement, 11 patients had the catheter successfully removed. In the follow-up of 6 - 24 months (median: 10 months), patency of bile duct was preserved in 9 of 11 patients, and recurrent stenosis was seen in 2 patients. A severe complication with biliary artery branch rupture and massive hemobilia was seen in 1 patient during balloon dilation. Of the 9 patients only treated with 1 - 12 months (median: 6 months) of PTCD catheter placement, 7 patients had the catheter successfully removed. In the follow-up of 5 - 18 months (median: 8 months), patency of bile duct was preserved in 5 of 7 patients, and recurrent stenosis was seen in 2 patients. No severe complication occurred.

CONCLUSIONS

When endoscopy therapy is failed or the patient can't undergo endoscopy therapy, the percutaneous balloon dilation and PTCD catheter maintenance method is an effective alternative therapeutic approach in the treatment of benign biliary strictures. The moderate benign biliary stricture may be effectively treated only by the PTCD catheter maintenance method.

摘要

目的

探讨经皮球囊扩张术及经皮经肝胆道引流(PTCD)导管置入术在良性胆管狭窄治疗中的价值。

方法

回顾性分析2005年6月至2011年6月在北京协和医院就诊的21例良性胆管狭窄患者的临床资料,其中12例重度狭窄(狭窄>70%)患者采用经皮球囊扩张术并在狭窄处放置PTCD导管,另外9例中度狭窄(狭窄<70%)患者仅采用PTCD导管置入术。

结果

12例行球囊扩张术并放置PTCD导管6 - 12个月(中位时间:9个月)的患者中,11例成功拔除导管。在6 - 24个月(中位时间:10个月)的随访中,11例患者中有9例胆管保持通畅,2例出现复发性狭窄。1例患者在球囊扩张术中出现严重并发症,即肝动脉分支破裂并大量胆道出血。9例仅接受PTCD导管置入术1 - 12个月(中位时间:6个月)的患者中,7例成功拔除导管。在5 - 18个月(中位时间:8个月)的随访中,7例患者中有5例胆管保持通畅,2例出现复发性狭窄。未发生严重并发症。

结论

当内镜治疗失败或患者无法接受内镜治疗时,经皮球囊扩张术及PTCD导管置入术是治疗良性胆管狭窄的一种有效的替代治疗方法。中度良性胆管狭窄仅采用PTCD导管置入术可能有效治疗。

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