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肝移植中的胆管狭窄:使用自膨式Z形支架治疗

Biliary strictures in hepatic transplantation: treatment with self-expanding Z stents.

作者信息

Petersen B D, Maxfield S R, Ivancev K, Uchida B T, Rabkin J M, Rösch J

机构信息

Dotter Interventional Institute, Oregon Health Sciences University, Portland 97201, USA.

出版信息

J Vasc Interv Radiol. 1996 Mar-Apr;7(2):221-8. doi: 10.1016/s1051-0443(96)70765-0.

Abstract

PURPOSE

To determine the long-term results of Gianturco-Rösch Z (GRZ) stent placement for the treatment of recurrent, benign biliary strictures in liver transplant recipients.

MATERIALS AND METHODS

During a 5-year period, eight orthotopic liver transplant recipients underwent transhepatic placement of GRZ stents to treat 12 recurrent biliary strictures (six anastomotic, six intrahepatic). Prior treatment of 11 strictures with balloon dilation therapy had failed. Patients were followed up for 1-65 months.

RESULTS

Stent placement was successful in all patients. Stent position remained stable in all but one patient. Three patients died (1, 25, and 28 months after stent placement), all with patent stents. Four patients required no further biliary intervention. Two of the other four patients needed intermittent biliary balloon dilation with removal of bile duct debris. The third patient had a stable, nonobstructing stenosis in the stent. The fourth passed his stents and needed no further intervention.

CONCLUSION

GRZ stents are useful in patients who are refractory to repetitive balloon dilation of biliary strictures or who are poor surgical candidates.

摘要

目的

确定使用Gianturco-Rösch Z(GRZ)支架治疗肝移植受者复发性良性胆管狭窄的长期效果。

材料与方法

在5年期间,8例原位肝移植受者接受了经肝GRZ支架置入术,以治疗12处复发性胆管狭窄(6处吻合口狭窄,6处肝内狭窄)。11处狭窄先前接受球囊扩张治疗失败。对患者进行了1至65个月的随访。

结果

所有患者支架置入均成功。除1例患者外,所有患者的支架位置均保持稳定。3例患者死亡(分别在支架置入后1、25和28个月),所有患者的支架均通畅。4例患者无需进一步的胆道干预。另外4例患者中的2例需要间歇性胆道球囊扩张并清除胆管碎片。第3例患者支架内有稳定的、无阻塞性狭窄。第4例患者排出了支架,无需进一步干预。

结论

GRZ支架对于胆管狭窄反复球囊扩张治疗无效或手术条件较差的患者有用。

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