Linke Stephan, Bartsch Udo, Richard Gisbert, Klemm Maren
Department of Ophthalmology, University Hospital, Hamburg-Eppendorf, Hamburg, Germany.
Graefes Arch Clin Exp Ophthalmol. 2007 Feb;245(2):309-12. doi: 10.1007/s00417-006-0310-x.
Deposits in various layers of the cornea might result from long-term medical therapy, photorefractive surgery, and longterm use of contact lenses or corneal dystrophies.
A 46-year-old woman was referred to our department with the suspected diagnosis of posterior polymorphous dystrophy. Slit-lamp biomicroscopy revealed bilateral small-sized deposits in the posterior part of the cornea. In vivo confocal microscopy was performed to evaluate these deposits in detail.
In vivo confocal microscopy of the cornea identified hyperreflec-tive "dot-like" structures in the deep stromal layer and anterior to the endothelial cell layer. The morphology and number of keratocytes of the posterior stroma and of endothelial cells appeared normal.
In vivo confocal microscopy is a very useful tool to analyze and visualize pre-endothelial deposits. Because there is no family history of corneal disease, the exact origin of the pre-endothelial deposits in our case remains unclear.
角膜各层的沉积物可能源于长期药物治疗、屈光性角膜手术、长期使用隐形眼镜或角膜营养不良。
一名46岁女性因疑似后弹力层角膜内皮营养不良被转诊至我科。裂隙灯生物显微镜检查发现角膜后部有双侧小沉积物。进行了活体共聚焦显微镜检查以详细评估这些沉积物。
角膜活体共聚焦显微镜检查在深基质层和内皮细胞层前方发现高反射性“点状”结构。后基质层的角膜细胞和内皮细胞的形态及数量看起来正常。
活体共聚焦显微镜检查是分析和观察内皮前沉积物的非常有用的工具。由于该病例无角膜疾病家族史，内皮前沉积物的确切来源仍不清楚。
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