Nuti R, Martini G, Merlotti D, Valleggi F, De Paola V, Gennari L
Department of Internal Medicine, University of Siena, Siena, Italy.
J Endocrinol Invest. 2005;28(10 Suppl):52-60.
Osteoporosis is the most prevalent metabolic bone disease among developed countries. Although bone mass and density are certainly determined by various concurrent factors such as genetics, hormones, life-style and the environment, and although the genetic program has a critical role in growth and in bone peak development, for their realization an adequate nutritional intake of nutrients and regular exercise are always necessary and may represent a way to prevent osteoporosis and fractures. Exercise and especially high-impact sport activity during growth and adolescence increases bone mineral density (BMD) in weight-loaded skeletal regions. Aerobics, weight bearing and resistance exercises may also be effective in increasing BMD in post-menopausal women. Even though most of the research on nutritional components has focused almost exclusively on calcium and vitamin D, there is now considerable interest in the effects of a variety of other nutrients on bone status.
骨质疏松症是发达国家中最普遍的代谢性骨病。尽管骨量和骨密度当然由多种并存因素决定,如遗传、激素、生活方式和环境,尽管遗传程序在生长和骨峰值发育中起关键作用,但要实现这些,充足的营养摄入和定期锻炼总是必要的,且可能是预防骨质疏松症和骨折的一种方法。在生长和青春期进行锻炼,尤其是高强度的体育活动,可增加负重骨骼区域的骨矿物质密度(BMD)。有氧运动、负重运动和抗阻运动对增加绝经后女性的骨密度也可能有效。尽管大多数关于营养成分的研究几乎都只集中在钙和维生素D上,但现在人们对多种其他营养素对骨骼状态的影响也有了相当大的兴趣。