Rogers B A, Johnstone D J
Department of Trauma & Orthopaedics, Stoke Mandeville Hospital, Buckinghamshire, UK.
Ann R Coll Surg Engl. 2006 Mar;88(2):199-201. doi: 10.1308/003588406X82952.
This prospective audit studies the use of cross-matched blood in 301 patients over a 1-year period undergoing total knee (TKR) and total hip replacement (THR) surgery in an orthopaedic unit.
Analysis over the first 6 months revealed a high level of unnecessary cross-matched blood. The following interventions were introduced: (i) to cease routine cross-matching for THR; (ii) all patients to have a check full blood count on day 2 after surgery; and (iii) Hb < 8 g/dl to be considered as the trigger for transfusion in patients over 65 years and free from significant co-morbidity. These changes are in accordance with published national guidelines [Anon. Guidelines for the clinical use of red cell transfusions. Br J Haematol 2001; 113: 24-31].
In the next 6 months, the number of units cross-matched but not transfused fell by 96% for THR, and the cross-match transfusion (C:T) ratio reduced from 3.21 to 1.62. Reductions were also observed for the TKR cohort. These results provide evidence of a substantial risk and cost benefit in the use of this limited resource. A telephone survey of 44 hospitals revealed that 20 hospitals routinely cross-matched blood for THR and 11 do so for TKR.
Changes can be made to the Maximum Surgical Blood Ordering Schedules (MSBOS) in other orthopaedic units according to national guidelines.
本前瞻性审计研究了在骨科病房进行全膝关节置换术(TKR)和全髋关节置换术(THR)的301例患者在1年期间交叉配血的使用情况。
对前6个月的分析显示不必要交叉配血的比例很高。因此采取了以下干预措施:(i)停止对THR进行常规交叉配血;(ii)所有患者在术后第2天进行全血细胞计数检查;(iii)对于65岁以上且无重大合并症的患者,血红蛋白(Hb)<8 g/dl被视为输血触发指标。这些改变符合已发布的国家指南[匿名。红细胞输血临床应用指南。《英国血液学杂志》2001年;113:24 - 31]。
在接下来的6个月中,THR交叉配血但未输血的单位数量下降了96%,交叉配血输血(C:T)比例从3.21降至1.62。TKR队列也有下降。这些结果证明了在使用这种有限资源时存在重大风险和成本效益。对44家医院的电话调查显示,20家医院对THR常规进行交叉配血,11家对TKR进行交叉配血。
其他骨科病房可根据国家指南对最大手术用血预订计划(MSBOS)进行调整。