比较静脉注射或关节腔内注射氨甲环酸在不使用止血带的同期双侧膝关节置换手术中减少失血的疗效。
Comparing the efficacy of intravenous or intra-articular tranexamic acid in reducing blood loss in simultaneous bilateral knee replacement surgery without the use of tourniquet.
作者信息
Arora Mridul, Singh Saurabh, Gupta Varun, Dongre Ashutosh, Shetty Vijay
机构信息
Hiranandani Orthopaedic Medical Education (HOME), Dr L H Hiranandani Hospital, Hillside Avenue, Hiranandani Gardens, Powai, Mumbai, 400076, India.
出版信息
Eur J Orthop Surg Traumatol. 2018 Oct;28(7):1417-1420. doi: 10.1007/s00590-018-2194-y. Epub 2018 Mar 29.
PURPOSE
To compare the effect of intravenous or intra-articular route of administration of tranexamic acid in reducing the blood loss in simultaneous bilateral total knee replacement surgeries performed without the use of tourniquets.
METHODS
Prospective cohort study of 30 consecutive patients grouped into two groups; Group 1: intravenous group and group 2: intra-articular group. Two outcome measures were studied; mean drop in post-operative haemoglobin and need for blood transfusion in both groups.
RESULTS
No significant difference in mean drop of haemoglobin and need for blood transfusion in both groups.
CONCLUSION
Route of administration of tranexamic acid does not influence on the mean drop of haemoglobin and need for blood transfusion in simultaneous bilateral total knee replacement surgeries performed without the use of tourniquet.
目的
比较在不使用止血带的双侧同期全膝关节置换手术中，静脉注射与关节腔内注射氨甲环酸对减少失血的效果。
方法
对30例连续患者进行前瞻性队列研究，分为两组；第1组：静脉注射组，第2组：关节腔内注射组。研究了两项结果指标；两组术后血红蛋白的平均下降幅度和输血需求。
结果
两组在血红蛋白平均下降幅度和输血需求方面无显著差异。
结论
在不使用止血带的双侧同期全膝关节置换手术中，氨甲环酸的给药途径对血红蛋白的平均下降幅度和输血需求无影响。
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