Dilbaz Berna, Bayoglu Yesim, Oral Serdar, Cavusoglu Deniz, Uluoglu Omer, Dilbaz Serdar
Department of Endoscopic Surgery, SSK (Social Security Organization), Maternity and Women's Health Training Hospital, Ankara, Turkey.
Surg Laparosc Endosc Percutan Tech. 2006 Feb;16(1):58-61. doi: 10.1097/01.sle.0000202194.51699.2a.
The case report of a 55-year-old woman with an incidentally diagnosed urinary paraganglioma of the bladder is presented. The patient had no irritative voiding symptoms, hematuria or hypertension. She was diagnosed to have an immobile solid mass on the left side neighboring the lower segment of the uterus. Transvaginal ultrasonography revealed a well-limited ovoid mass with solid and cystic areas adjacent to the urinary bladder and the uterus. Tumor markers were within normal range. Laparoscopy was performed for the treatment of the mass and complete excision of the cyst was accomplished. Frozen section was performed revealing a benign cystic structure but the identification of the origin was left to definitive histopathological examination which showed paraganglioma of the bladder. Immunohistochemically, the tumor cells were strongly positive for chromogranin A and synaptophysin and there was focal positiveness for neuron specific enolase although vimentin and cytokeratin were negative.
本文报告了一例55岁女性膀胱副神经节瘤的病例，该肿瘤为偶然发现。患者无刺激性排尿症状、血尿或高血压。诊断发现子宫下段左侧有一个固定的实性肿块。经阴道超声检查发现一个边界清晰的卵圆形肿块，有实性和囊性区域，毗邻膀胱和子宫。肿瘤标志物在正常范围内。为治疗该肿块进行了腹腔镜检查，并完整切除了囊肿。进行了冰冻切片检查，显示为良性囊性结构，但起源的确定留待最终的组织病理学检查，结果显示为膀胱副神经节瘤。免疫组织化学检查显示，肿瘤细胞嗜铬粒蛋白A和突触素呈强阳性，神经元特异性烯醇化酶呈局灶阳性，波形蛋白和细胞角蛋白呈阴性。
