Johnson Sheri L, McMurrich Stephanie L, Yates Marisa
Department of Psychology, University of Miami, P.O. Box 248185, Coral Gables, FL 33124-0751, USA.
Suicide Life Threat Behav. 2005 Dec;35(6):681-9. doi: 10.1521/suli.2005.35.6.681.
People with bipolar disorder are at high suicide risk. The literature suggests that suicidality is predicted by higher symptom severity and less use of pharmacological agents, but few studies have examined the joint contributions of these variables. The present study examines the conjoint contribution of symptom severity and pharmacological treatment to suicidal ideation and behavior among participants with bipolar disorder. The model was able to account for 53% of the variance in suicidality scores. Depression, mixed state, and hopelessness were significantly associated with suicidality. All other variables were nonsignificant once symptom severity had been controlled. Implications for future research are described.
双相情感障碍患者自杀风险很高。文献表明，自杀倾向可通过更高的症状严重程度和较少使用药物来预测，但很少有研究考察这些变量的共同作用。本研究考察了症状严重程度和药物治疗对双相情感障碍患者自杀观念和行为的联合作用。该模型能够解释自杀倾向得分中53%的方差变异。抑郁、混合状态和绝望与自杀倾向显著相关。一旦控制了症状严重程度，所有其他变量均无显著意义。文中描述了对未来研究的启示。
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