双相情感障碍不同阶段的自杀行为。

Suicidal behaviour during different phases of bipolar disorder.

作者信息

Valtonen Hanna M, Suominen Kirsi, Mantere Outi, Leppämäki Sami, Arvilommi Petri, Isometsä Erkki

机构信息

Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland.

出版信息

J Affect Disord. 2007 Jan;97(1-3):101-7. doi: 10.1016/j.jad.2006.05.033. Epub 2006 Jul 11.

DOI:10.1016/j.jad.2006.05.033

PMID:16837060

Abstract

BACKGROUND

There are no previous studies comparing the prevalence and risk factors for suicidal behaviour during different phases of bipolar disorder.

METHODS

In the Jorvi Bipolar Study (JoBS), 1630 psychiatric in- and outpatients were screened for bipolar disorders with the Mood Disorder Questionnaire. Using SCID I and II interviews, 191 patients were diagnosed with bipolar disorders (90 bipolar I, 101 bipolar II). Suicidal ideation was measured using the Scale for Suicidal Ideation (SSI). Prevalence and risk factors for ideation and attempts during different phases (depressive, mixed, depressive mixed and hypomanic/manic phases) were investigated.

RESULTS

There were marked differences between phases regarding suicide attempts and level of suicidal ideation. Hopelessness predicted suicidal behaviour during the depressive phase, whereas a subjective rating of severity of depression and younger age predicted suicide attempts during mixed phases.

LIMITATIONS

The relatively small sample size in some phases.

CONCLUSIONS

Suicidal behaviour varied markedly between different phases of BD. Suicide attempts and suicidal ideation were related to phases which are associated with depressive aspects of the illness. Hopelessness and severity of depression were key indicators of risk in all phases.

摘要

背景

既往尚无研究比较双相情感障碍不同阶段自杀行为的患病率及危险因素。

方法

在约尔维双相情感障碍研究（JoBS）中，使用心境障碍问卷对1630名精神科门诊及住院患者进行双相情感障碍筛查。通过SCID I和II访谈，191名患者被诊断为双相情感障碍（90例双相I型，101例双相II型）。使用自杀意念量表（SSI）测量自杀意念。研究不同阶段（抑郁、混合、抑郁混合及轻躁狂/躁狂阶段）的自杀意念及自杀未遂的患病率和危险因素。