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早产和足月婴儿胃慢波的发育及喂养的影响

Development of gastric slow waves and effects of feeding in pre-term and full-term infants.

作者信息

Zhang J, Ouyang H, Zhu H B, Zhu H, Lin X, Co E, Hayes J, Chen J D Z

机构信息

Division of Gastroenterology, University of Texas Medical Branch at Galveston, 77555, USA.

出版信息

Neurogastroenterol Motil. 2006 Apr;18(4):284-91. doi: 10.1111/j.1365-2982.2006.00756.x.

Abstract

The aims of this study were to investigate the difference in developmental process of gastric slow waves and the effects of feeding in pre-term and full-term infants. Twenty-six pre-term and 31 full-term infants were enrolled in the study. Gastric myoelectrical activity was recorded using electrogastrography (EGG) from birth to month 6. An increase in the % of 2-4 cpm slow waves was noted in both pre-term (P < 0.01) and full-term infants (P < 0.04) from birth to month 4. The pre-term infants showed a reduced dominant EGG power at certain points of the study. (3) Breast or formula feeding resulted in no difference in the EGG in the full-term infants and showed a difference in the postprandial dominant power of the EGG in the pre-term infants only at month 2 after birth (P < 0.05) but not at other times. The gastric slow wave in pre-term infants is of a significantly reduced amplitude but similar rhythmicity. The method of feeding has no effects on the EGG in full-term infants and minimal effects (may be of non-clinical significance) on the EGG in pre-term infants as the difference was noted only at one time point during the 6-month follow-up study.

摘要

本研究的目的是调查早产和足月婴儿胃慢波发育过程的差异以及喂养的影响。26名早产婴儿和31名足月婴儿参与了该研究。从出生到6个月,使用胃电图(EGG)记录胃肌电活动。从出生到4个月,早产婴儿(P < 0.01)和足月婴儿(P < 0.04)的2 - 4次/分钟慢波百分比均有所增加。在研究的某些时间点,早产婴儿的EGG主功率降低。(3)母乳喂养或配方奶喂养对足月婴儿的EGG没有差异,仅在出生后2个月时,对早产婴儿餐后EGG主功率有差异(P < 0.05),其他时间无差异。早产婴儿的胃慢波振幅明显降低,但节律相似。喂养方式对足月婴儿的EGG没有影响,对早产婴儿的EGG影响极小(可能无临床意义),因为在6个月的随访研究中仅在一个时间点发现差异。

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