Messa C, Di Muzio N, Picchio M, Gilardi M C, Bettinardi V, Fazio F
Center of Molecular Bioimaging, University of Milano-Bicocca, Milan, Italy.
Q J Nucl Med Mol Imaging. 2006 Mar;50(1):4-14.
This article reviews the state of the art of PET/CT applications in radiotherapy, specifically its use in disease staging, patient selection, treatment planning and treatment evaluation. Diseases for which radiotherapy with radical intent is indicated will be considered, as well as those in which PET/CT may actually change the course of disease. The methodological and technological aspects of PET/CT in radiotherapy are discussed, focusing on the problem of target volume definition with CT and PET functional imaging and the problem of tumor motion with respect to imaging and dose delivery.
本文综述了正电子发射断层显像/计算机断层扫描（PET/CT）在放射治疗中的应用现状，特别是其在疾病分期、患者选择、治疗计划和治疗评估中的应用。将考虑有根治性放疗指征的疾病，以及PET/CT可能实际改变疾病进程的疾病。讨论了PET/CT在放射治疗中的方法学和技术方面，重点关注CT和PET功能成像的靶区定义问题以及肿瘤在成像和剂量传递方面的运动问题。
