Department of Biology, Wayne State University, Detroit, Michigan 48202.
Infect Immun. 1970 Jan;1(1):78-9. doi: 10.1128/iai.1.1.78-79.1970.
Of 235 strains of coagulase-positive Staphylococcus aureus studied, 221 or 94% were inhibited by 1.5 x 10(-8)m sodium borate, whereas only 6 of 57 (10.5%) coagulase-negative strains were inhibited by the same borate concentration. Four of the six coagulase-negatives were food poisoning strains and one was a hospital pathogen. Borate sensitivity was found to correlate well with lysozyme and alpha-toxin production by coagulase-positive strains.
在研究的 235 株凝固酶阳性金黄色葡萄球菌中,有 221 株(94%)被 1.5 x 10(-8)m 硼酸钠抑制,而在 57 株凝固酶阴性菌中,只有 6 株(10.5%)被相同浓度的硼酸钠抑制。这 6 株凝固酶阴性菌中有 4 株是食物中毒菌株,1 株是医院病原体。研究发现,硼酸钠的敏感性与凝固酶阳性菌株产生的溶菌酶和α-毒素密切相关。