葡萄球菌肠毒素 B 与细胞培养物的相互作用 I. 血清和检测程序的影响。
Interaction of staphylococcal enterotoxin B with cell cultures I. Effect of serum and testing procedures.
机构信息
Department of Medical Microbiology, College of Medicine, The University of Vermont, Burlington, Vermont 05401.
出版信息
Infect Immun. 1970 May;1(5):455-8. doi: 10.1128/iai.1.5.455-458.1970.
The cytopathic effect of staphylococcal enterotoxin B upon mammalian cell cultures is expressed fully only if the cultures are grown in human serum-supplemented media. Little cytotoxicity is seen if the cells are grown in horse serum-supplemented media and none is seen if the cells are grown in calf serum-supplemented media. The cytotoxicity of the toxin is reversible at any stage of intoxication. Cytotoxicity is rarely seen before 5 hr and is most often not evident before 8 hr. Cytoxicity is not lethal.
金黄色葡萄球菌肠毒素 B 对哺乳动物细胞培养物的细胞病变效应只有在细胞生长于用人血清补充的培养基中时才能完全表达。如果细胞生长在马血清补充的培养基中，则几乎观察不到细胞毒性，如果细胞生长在小牛血清补充的培养基中，则根本观察不到细胞毒性。毒素的细胞毒性在任何中毒阶段都是可逆的。在 5 小时之前很少观察到细胞毒性，在 8 小时之前通常也观察不到。细胞毒性不是致命的。
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