细菌脂多糖对大肠杆菌素E2活性的抑制作用。
Inhibition of colicin e2 activity by bacterial lipopolysaccharide.
作者信息
Chang Y Y, Hager L P
机构信息
Department of Biochemistry, University of Illinois, Urbana, Illinois 61801.
出版信息
J Bacteriol. 1970 Dec;104(3):1106-9. doi: 10.1128/jb.104.3.1106-1109.1970.
Abstract
Lipopolysaccharide isolated from colicin E2-sensitive Escherichia coli and from "receptor-minus" mutants inhibits the activity of colicin E2. Lipid A and the polysaccharide fraction obtained by mild acid hydrolysis of lipopolysaccharide are inactive either alone or when tested in combination. Periodate oxidation of lipopolysaccharide destroys over 85% of its inhibition activity.
摘要
从对大肠杆菌素E2敏感的大肠杆菌及“无受体”突变体中分离出的脂多糖会抑制大肠杆菌素E2的活性。脂多糖经温和酸水解得到的脂质A和多糖部分单独或联合测试时均无活性。脂多糖经高碘酸盐氧化后，其抑制活性丧失超过85%。
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