O'Leary M J, Shelton C, Giddings N A, Kwartler J, Brackmann D E
House Ear Clinic, University of Southern California School of Medicine, Los Angeles.
Laryngoscope. 1991 Oct;101(10):1038-43. doi: 10.1288/00005537-199110000-00002.
Since Guild first discovered glomus bodies in the middle ear, the diagnostic evaluation and therapy of glomus tympanicum tumors have remained challenging. This study describes 73 cases diagnosed as glomus tympanicum tumors over the past 30 years. During this period, imaging techniques have markedly improved, and surgical approaches have evolved and been refined. These 73 cases were reviewed from a clinical perspective involving presentation, diagnostic evaluation, and therapeutic management. Pulsatile tinnitus was the primary symptom in over half the patients, followed by hearing loss in one third. The physical exam rarely revealed a circumferential view of the lesion, emphasizing the necessity of further diagnostic evaluation. High-resolution computerized tomography (CT) is currently the radiographic study of choice. A transmastoid surgical approach with extended facial recess was most commonly employed. Extension to the jugular bulb or internal carotid was rare, and no intraoperative complications of catecholamine secretion were noted. Postoperative complications were few, and the overall residual/recurrence rate was less than 5%. Additional clinical insights may assist in the management of these rare but fascinating tumors.
自从吉尔首次在中耳发现球瘤以来,鼓室球瘤的诊断评估和治疗一直具有挑战性。本研究描述了过去30年中诊断为鼓室球瘤的73例病例。在此期间,成像技术有了显著改进,手术方法也不断发展和完善。从临床表现、诊断评估和治疗管理等临床角度对这73例病例进行了回顾。搏动性耳鸣是半数以上患者的主要症状,其次三分之一患者有听力损失。体格检查很少能看到病变的全貌,这强调了进一步诊断评估的必要性。高分辨率计算机断层扫描(CT)是目前首选的影像学检查。最常用的手术方法是经乳突扩展面神经隐窝入路。侵犯颈静脉球或颈内动脉的情况很少见,术中未发现儿茶酚胺分泌的并发症。术后并发症很少,总体残留/复发率不到5%。更多的临床见解可能有助于管理这些罕见但引人入胜的肿瘤。