Simícková M, Lang B A, Stratil P, Vermousek I, Rejthar A, Cernoch M, Pacovský Z
Masaryk Memorial Cancer Institute, Brno, Czechoslovakia.
Neoplasma. 1991;38(4):407-13.
The concentration of carcinoembryonic antigen and alpha-lactalbumin in tumor tissue cytosol were analyzed in a group of 19 tumors of cystosarcoma phyllodes type. Both antigens were also localized in the tissue of identical tumors by means of immunohistochemical procedure. The cytosol levels of both proteins were found to be higher in the histologically defined malignant type of phylloid tumors. This group was also characterized by the simultaneous occurrence of both antigens. We did not manage to prove any relationship between the presence of alpha-lactalbumin and the steroid hormone receptor positivity in tumor tissue.
对一组19例叶状囊肉瘤型肿瘤组织胞质溶胶中的癌胚抗原和α-乳白蛋白浓度进行了分析。还通过免疫组织化学方法将这两种抗原定位在相同肿瘤的组织中。发现这两种蛋白质的胞质溶胶水平在组织学定义的恶性叶状肿瘤类型中更高。该组的特征还在于两种抗原同时出现。我们未能证明α-乳白蛋白的存在与肿瘤组织中类固醇激素受体阳性之间存在任何关系。