女性下生殖道湿疣及癌前病变中乳头瘤病毒感染的免疫组化显示
Immunohistochemical demonstration of papillomavirus infection in condylomatous and preneoplastic lesions of the lower female genital tract.
作者信息
Andrade L A, Oyakawa N, Vassallo J
机构信息
Department of Pathology, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Sâo Paulo, Brazil.
出版信息
Pathologica. 1991 May-Jun;83(1085):301-6.
PMID:1656376
Abstract
An immunoperoxidase study of 250 cases of condyloma of the female genital tract showed HPV expression in 45% of the cases. The flat form was the most frequent (191/250 cases). Condylomatous lesions were associated with dysplasia, in situ or micro-invasive carcinoma in 43% of the cases. The results support the role of the HPV as a possible carcinogenic agent in the female genital tract.
摘要
一项对250例女性生殖道尖锐湿疣的免疫过氧化物酶研究显示，45%的病例中存在人乳头瘤病毒（HPV）表达。扁平型最为常见（250例中有191例）。43%的病例中湿疣样病变与发育异常、原位癌或微浸润癌相关。这些结果支持HPV作为女性生殖道可能致癌因子的作用。
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