Bann James G, Cegelski Lynette, Hultgren Scott J
Department of Chemistry, Wichita State University, Wichita, Kansas 67260, USA.
Cell. 2006 Mar 24;124(6):1119-21. doi: 10.1016/j.cell.2006.03.007.
In this issue of Cell, it is demonstrated that the low-density lipoprotein receptor-related protein 6 (LRP6) promotes endocytosis of the anthrax toxin into cells. LRP6 acts as a coreceptor with either TEM8 or CMG2, the two previously identified receptors for anthrax toxin.
在本期《细胞》杂志中,研究表明低密度脂蛋白受体相关蛋白6(LRP6)可促进炭疽毒素内吞进入细胞。LRP6与TEM8或CMG2作为共受体发挥作用,TEM8和CMG2是之前已确定的两种炭疽毒素受体。